baquiloprim
baquiloprim structure
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Common Name | baquiloprim | ||
|---|---|---|---|---|
| CAS Number | 102280-35-3 | Molecular Weight | 308.381 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 567.9±60.0 °C at 760 mmHg | |
| Molecular Formula | C17H20N6 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 297.2±32.9 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Eimeria alabamensis coccidiosis in grazing calves: control by a long-acting baquiloprim/sulphadimidine bolus.
Appl. Parasitol. 37(3) , 168-76, (1996) The excretion of Eimeria oocysts, the faecal dry matter and the weight gain of three groups of 12 calves, were compared during their first 20 days of grazing on a pasture known to have been contaminated with oocysts of Eimeria alabamensis during the previous ... |
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Oral bioavailability and pharmacokinetics of baquiloprim in dwarf goats.
Res. Vet. Sci. 58(3) , 268-71, (1995) The pharmacokinetics of baquiloprim at a dose of 8 mg kg-1 bodyweight were determined after its intravenous and intra-ruminal administration to seven healthy female dwarf goats. After intravenous injection, the plasma elimination curve showed a rapid distribu... |
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Prevention of Eimeria alabamensis coccidiosis by a long-acting baquiloprim/sulphadimidine bolus.
Vet. Parasitol. 74(2-4) , 143-52, (1998) Twelve calves aged 6-10 months, and 12 calves aged 10-16 months were turned out onto a permanent pasture known to have been contaminated with oocysts of Eimeria alabamensis during the previous year. Two days after turnout, six of the older calves and six of t... |
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Administration of a bolus formulation of baquiloprim and sulphadimidine to calves: plasma concentration--time profiles and efficacy in suppressing experimental pneumonic pasteurellosis.
Vet. Microbiol. 38(3) , 255-62, (1994) After administration of a bolus containing 0.8 g baquiloprim and 7.2 g sulphadimidine to six calves, plasma concentrations of these compounds exceeded MICs for Pasteurella haemolytica from about 3 hours to at least 48 hours. Experimental infection of three ca... |
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Baquiloprim, a new antifolate antibacterial: in vitro activity and pharmacokinetic properties in cattle.
Res. Vet. Sci. 54(3) , 372-8, (1993) During examination of the half-lives in cattle of a series of 5-substituted diaminobenzyl-pyrimidines, it was found that replacement of the phenyl ring of trimethoprim (TMP) by bicyclic structures, particularly a quinolyl group, led to increases in half-life.... |
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Comparison of danofloxacin with baquiloprim/sulphadimidine for the treatment of experimentally induced Escherichia coli diarrhoea in calves.
Vet. Rec. 143(10) , 273-6, (1998) Thirty-eight, one- to two-week-old calves with experimentally induced Escherichia coli diarrhoea were randomly assigned to three treatment groups. Two groups of 15 calves were treated intramuscularly once daily for three days with either danofloxacin mesylate... |
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Pharmacokinetics of baquiloprim and sulphadimidine in pigs after intramuscular administration.
Res. Vet. Sci. 57(1) , 69-74, (1994) Baquiloprim, a novel 5-substituted 2, 4-diaminopyrimidine, has been developed specifically for veterinary use. It has been formulated as an injectable preparation and combined with sulphadimidine to exploit the synergistic activity of the two antibacterial ag... |