3-Oxocyclopentanecarboxylic acid

3-Oxocyclopentanecarboxylic acid Structure
3-Oxocyclopentanecarboxylic acid structure
Common Name 3-Oxocyclopentanecarboxylic acid
CAS Number 98-78-2 Molecular Weight 128.126
Density 1.3±0.1 g/cm3 Boiling Point 300.6±35.0 °C at 760 mmHg
Molecular Formula C6H8O3 Melting Point 59-62 °C(lit.)
MSDS Chinese USA Flash Point 149.9±22.4 °C

Stereoselective hydroxylation of an achiral cyclopentanecarboxylic acid derivative using engineered P450s BM-3.

Chem. Commun. (Camb.) , 2597, (2005)

Substrate engineered, achiral carboxylic acid derivative was biohydroxylated with various mutants of cytochrome P450 BM-3 to give two out of the four possible diastereoisomers in high de and ee. The BM-3 mutants exhibit up to 9200 total turnovers for hydroxyl...