PROTEIN TYROSINE PHOSPHATASE SUBSTRATE
PROTEIN TYROSINE PHOSPHATASE SUBSTRATE structure
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Common Name | PROTEIN TYROSINE PHOSPHATASE SUBSTRATE | ||
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| CAS Number | 104077-19-2 | Molecular Weight | 1622.75 | |
| Density | 1.51±0.1 g/cm3(Predicted) | Boiling Point | N/A | |
| Molecular Formula | C72H107N19O24 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
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Phosphorylation of synthetic insulin receptor peptides by the insulin receptor kinase and evidence that the preferred sequence containing Tyr-1150 is phosphorylated in vivo.
J. Biol. Chem. 261 , 10000, (1986) Three peptides were synthesized corresponding to potential autophosphorylation sites of the beta subunit of the human insulin receptor. These were peptide 1150 corresponding to amino acids 1142-1153 of the pro-receptor, peptide 960 corresponding to amino acid... |
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Assay of phosphotyrosyl protein phosphatase using synthetic peptide 1142-1153 of the insulin receptor.
FEBS Lett. 237 , 137, (1988) Synthetic peptide 1142-1153 of the insulin receptor was phosphorylated on tyrosine by the insulin receptor and found to be a potent substrate for dephosphorylation by rat liver particulate and soluble phosphotyrosyl protein phosphatases. Apparent Km values we... |
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Intrinsic kinase activity of the insulin receptor. The intact (alpha 2 beta 2) insulin receptor from rat liver contains a kinase domain with greater intrinsic activity than the intact insulin receptor from human placenta.
J. Biol. Chem. 264 , 602, (1989) We are interested in developing methods to rigorously characterize the intrinsic enzymatic activity of the insulin receptor. We have previously shown that the intact, kinase active form of the receptor can be separated from inactive forms isolated from human ... |
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Bannwarth, W., and Kitas, E.A.
Helv. Chim. Acta 75 , 707, (1992)
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