p-Fluorobenzotrifluoride
p-Fluorobenzotrifluoride structure
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Common Name | p-Fluorobenzotrifluoride | ||
|---|---|---|---|---|
| CAS Number | 402-44-8 | Molecular Weight | 164.100 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 104.4±35.0 °C at 760 mmHg | |
| Molecular Formula | C7H4F4 | Melting Point | −42-−41.7 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 10.6±0.0 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Synthesis of novel trifluoromethyl-bearing bifunctional acyl-acceptant arenes: 2,2'-bis(trifluoromethylated aryloxy)biphenyls.
J. Oleo Sci. 56(9) , 479-91, (2007) Novel bifunctional acyl-acceptant biphenyls bearing trifluoromethylated aroyloxy groups were successfully synthesized in high yields via TfOH-mediated electrophilic aromatic aroylation of fluorobenzene with CF(3)-bearing aroyl chlorides followed by nucleophil... |
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Absolute configurations and pharmacological activities of the optical isomers of fluoxetine, a selective serotonin-uptake inhibitor.
J. Med. Chem. 31(7) , 1412-7, (1988) Fluoxetine is a potent and selective inhibitor of the neuronal serotonin-uptake carrier and is a clinically effective antidepressant. Although fluoxetine is used therapeutically as the racemate, there appears to be a small but demonstrable stereospecificity a... |
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Synthesis and appetite suppressant activity of 1-aryloxy-2-substituted aminomethyltetrahydronaphthalenes as conformationally rigid analogues of fluoxetine.
Bioorg. Med. Chem. 14(8) , 2535-44, (2006) Several 1-aryloxy-2-substituted aminomethyltetrahydronaphthalenes (7-21) as conformationally rigid analogues of fluoxetine were synthesized and evaluated for their anorexigenic and antidepressant activities. For SAR studies the related acyclic analogues (22-2... |