2-Bromo-5-(trifluoromethyl)aniline

2-Bromo-5-(trifluoromethyl)aniline Structure
2-Bromo-5-(trifluoromethyl)aniline structure
Common Name 2-Bromo-5-(trifluoromethyl)aniline
CAS Number 454-79-5 Molecular Weight 240.020
Density 1.7±0.1 g/cm3 Boiling Point 243.1±40.0 °C at 760 mmHg
Molecular Formula C7H5BrF3N Melting Point 47-49°C
MSDS Chinese USA Flash Point 100.8±27.3 °C
Symbol GHS05
GHS05
Signal Word Danger

Hepatitis C virus NS3 protease inhibitors comprising a novel aromatic P1 moiety.

Bioorg. Med. Chem. 16(6) , 2955-67, (2008)

Inhibition of the hepatitis C virus (HCV) NS3 protease has emerged as an attractive approach to defeat the global hepatitis C epidemic. In this work, we present the synthesis and biochemical evaluation of HCV NS3 protease inhibitors comprising a non-natural a...