Fluvoxamine maleat
Fluvoxamine maleat structure
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Common Name | Fluvoxamine maleat | ||
|---|---|---|---|---|
| CAS Number | 61718-82-9 | Molecular Weight | 434.407 | |
| Density | N/A | Boiling Point | 370.6ºC at 760 mmHg | |
| Molecular Formula | C19H25F3N2O6 | Melting Point | 120-121.5ºC | |
| MSDS | Chinese USA | Flash Point | 177.9ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Tacrine sinusoidal uptake and biliary excretion in sandwich-cultured primary rat hepatocytes.
J. Pharm. Pharm. Sci. 17(3) , 427-38, (2014) PURPOSE. The knowledge of hepatic disposition kinetics of tacrine, a first cholinesterase inhibitor was approved by FDA for the treatment of Alzheimer's disease (AD), would help to understand its hepatotoxicity, its therapeutic effect, and improve the managem... |
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5-HTTLPR rs25531A > G differentially influence paroxetine and fluvoxamine antidepressant efficacy: a randomized, controlled trial.
J. Clin. Psychopharmacol. 33(1) , 131-2, (2013)
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Pharmacological profile of encounter-induced hyperactivity in isolation-reared mice.
Behav. Pharmacol. 26 , 681-90, (2015) We have recently found that isolation-reared mice show hyperactivity during an encounter with an intruder. However, it is not known whether encounter-induced hyperactivity may model some aspects of psychiatric disorders. The present study examined the pharmac... |
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Differential substitution for the discriminative stimulus effects of 3,4-methylenedioxymethamphetamine and methylphenidate in rats.
J. Pharmacol. Exp. Ther. 350(2) , 403-11, (2014) Previous studies have demonstrated that methylphenidate, MDMA (3,4-methylenedioxymethamphetamine), and other psychostimulants exert stimulant-like subjective effects in humans. Furthermore, MDMA and methylphenidate substitute for the discriminative stimulus e... |
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Regulator of G-protein signaling 6 (RGS6) promotes anxiety and depression by attenuating serotonin-mediated activation of the 5-HT(1A) receptor-adenylyl cyclase axis.
FASEB J. 28(4) , 1735-44, (2014) Targeting serotonin (5-HT) bioavailability with selective 5-HT reuptake inhibitors (SSRIs) remains the most widely used treatment for mood disorders. However, their limited efficacy, delayed onset of action, and side effects restrict their clinical utility. E... |
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An NMR investigation of the structure, function and role of the hERG channel selectivity filter in the long QT syndrome.
Biochim. Biophys. Acta 1828(6) , 1494-502, (2013) The human ether-a-go-go-related gene (hERG) voltage-gated K(+) channels are located in heart cell membranes and hold a unique selectivity filter (SF) amino acid sequence (SVGFG) as compared to other K(+) channels (TVGYG). The hERG provokes the acquired long Q... |
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Fluvoxamine alleviates seizure activity and downregulates hippocampal GAP-43 expression in pentylenetetrazole-kindled mice: role of 5-HT3 receptors.
Behav. Pharmacol. 26 , 369-82, (2015) Epilepsy has been documented to lead to many changes in the nervous system including cell loss and mossy fiber sprouting. Neuronal loss and aberrant neuroplastic changes in the dentate gyrus of the hippocampus have been identified in the pentylenetetrazole (P... |
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[Addition of fluvoxamine to clozapine: theory and practice].
Tijdschr. Psychiatr. 55(2) , 113-21, (2013) The addition of fluvoxamine to clozapine induces a rise of plasma concentrations of clozapine. This enables the prescription of a lower number of clozapine tablets, yet it attains sufficient clozapine plasma concentrations, and facilitates treatment adherence... |
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[Reaction on 'Addition of fluvoxamine to clozapine: theory and practice'. Reply to Sommer].
Tijdschr. Psychiatr. 55(4) , 310-2, (2013)
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[Reaction on 'Addition of fluvoxamine to clozapine: theory and practice'].
Tijdschr. Psychiatr. 55(4) , 309-10, (2013)
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