Cortisone acetate
Cortisone acetate structure
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Common Name | Cortisone acetate | ||
|---|---|---|---|---|
| CAS Number | 50-04-4 | Molecular Weight | 402.481 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 577.3±50.0 °C at 760 mmHg | |
| Molecular Formula | C23H30O6 | Melting Point | 237-240 °C(lit.) | |
| MSDS | USA | Flash Point | 197.3±23.6 °C | |
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Anti-angiogenic effect of Nelumbo nucifera leaf extracts in human umbilical vein endothelial cells with antioxidant potential.
PLoS ONE 10(2) , e0118552, (2015) Nelumbo nucifera Gaertn (Nymphaeaceae) has long been used as a traditional herb in Chinese, Japanese, Indian, and Korean medicinal practices since prehistoric times and flourishes today as the primary form of medicine. This study reports for the first time th... |
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Novel Aggregation Properties of Candida albicans Secreted Aspartyl Proteinase Sap6 Mediate Virulence in Oral Candidiasis.
Infect. Immun. 83 , 2614-26, (2015) Candida albicans, a commensal fungus of the oral microbiome, causes oral candidiasis in humans with localized or systemic immune deficiencies. Secreted aspartic proteinases (Saps) are a family of 10 related proteases and are virulence factors due to their pro... |
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The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps.
PLoS Pathog. 11 , e1005187, (2015) Of the over 250 Aspergillus species, Aspergillus fumigatus accounts for up to 80% of invasive human infections. A. fumigatus produces galactosaminogalactan (GAG), an exopolysaccharide composed of galactose and N-acetyl-galactosamine (GalNAc) that mediates adh... |
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Activity of potent and selective host defense peptide mimetics in mouse models of oral candidiasis.
Antimicrob. Agents Chemother. 58(7) , 3820-7, (2014) There is a strong need for new broadly active antifungal agents for the treatment of oral candidiasis that not only are active against many species of Candida, including drug-resistant strains, but also evade microbial countermeasures which may lead to resist... |
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Diet-induced weight loss has chronic tissue-specific effects on glucocorticoid metabolism in overweight postmenopausal women.
Int. J. Obes. 39 , 814-9, (2015) Tissue-specific glucocorticoid metabolism is altered in obesity, and may increase cardiovascular risk. This dysregulation is normalized by short-term calorie restriction and weight loss, an effect that varies with dietary macronutrient composition. However, t... |
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Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency.
J. Intern. Med. 275(2) , 104-15, (2014) Primary adrenal insufficiency (PAI), or Addison's disease, is a rare, potentially deadly, but treatable disease. Most cases of PAI are caused by autoimmune destruction of the adrenal cortex. Consequently, patients with PAI are at higher risk of developing oth... |
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Separation of corticosteroids by microemulsion EKC with diethyl L-tartrate as the oil phase.
Electrophoresis 28(20) , 3691-6, (2007) A novel microemulsion based on a mixture of diethyl L-tartrate (DET) and SDS was developed for the microemulsion EKC (MEEKC) determination of structurally related steroids. The system consisted of 0.5% w/w DET, 1.7% w/w SDS, 1.2% w/w 1-butanol, 89.6% w/w phos... |
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Comparative pharmacodynamics of posaconazole in neutropenic murine models of invasive pulmonary aspergillosis and mucormycosis.
Antimicrob. Agents Chemother. 58(11) , 6767-72, (2014) We used two established neutropenic murine models of pulmonary aspergillosis and mucormycosis to explore the association between the posaconazole area under the concentration-time curve (AUC)-to-MIC ratio (AUC/MIC) and treatment outcome. Posaconazole serum ph... |
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Carbon isotope ratio analysis of endogenous glucocorticoid urinary metabolites after cortisone acetate and adrenosterone administration for doping control.
Drug Test. Anal. 4(12) , 951-61, (2012) Glucocorticoids are listed on the World Anti-Doping Agency (WADA) Prohibited List of substances. The detection of the administration of hydrocortisone and cortisone is complicated by the fact that the human body also produces these steroids naturally. Gas chr... |
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Corticosteroid replacement therapy in hepatoadrenal syndrome: case report with a review of the literature.
Eur. J. Gastroenterol. Hepatol. 24(11) , 1344-7, (2012) In liver cirrhosis, hepatoadrenal syndrome has been described recently as a progressive impairment in the adrenocortical reserve, with deficient production or action of glucocorticoids resulting in adrenal insufficiency. Data on the treatment of this syndrome... |