1-Bromo-2,4-dinitrobenzene
1-Bromo-2,4-dinitrobenzene structure
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Common Name | 1-Bromo-2,4-dinitrobenzene | ||
|---|---|---|---|---|
| CAS Number | 584-48-5 | Molecular Weight | 247.00300 | |
| Density | 1.91g/cm3 | Boiling Point | 288.4ºC at 760 mmHg | |
| Molecular Formula | C6H3BrN2O4 | Melting Point | 71-73 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 128.2ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Glutathione metabolism in the HaCaT cell line as a model for the detoxification of the model sensitisers 2,4-dinitrohalobenzenes in human skin.
Toxicol. Lett. 237 , 11-20, (2015) Glutathione (GSH) is the most prominent antioxidant in cells and the co-factor of an important set of enzymes involved in the skin metabolic clearance system, glutathione S-transferases (GST). Here, we describe an LC-MS (liquid chromatography-mass spectroscop... |
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Time dependence in mixture toxicity with soft electrophiles: 1. Combined effects of selected SN2- and SNAr-reactive agents with a nonpolar narcotic.
Arch. Environ. Contam. Toxicol. 52(3) , 283-93, (2007) Frequently the toxicity of an organic chemical mixture is close to dose-additive, even when the agents are thought to induce toxicity at different molecular sites of action. These findings appear to conflict with the hypothesis that a strictly dose-additive c... |
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Sequence, catalytic properties and expression of chicken glutathione-dependent prostaglandin D2 synthase, a novel class Sigma glutathione S-transferase.
Biochem. J. 333 , 317-25, (1998) The Expressed Sequence Tag database has been screened for cDNA clones encoding prostaglandin D2 synthases (PGDSs) by using a BLAST search with the N-terminal amino acid sequence of rat GSH-dependent PGDS, a class Sigma glutathione S-transferase (GST). This re... |
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Nitroreductase independent mutagenicity of 1-halogenated-2,4-dinitrobenzenes.
Mutat. Res. 381(1) , 41-7, (1997) The 1-halogen substituted 2,4-dinitrobenzenes have been found to be mutagenic in Salmonella TA98 with an activity order of 1-fluoro > 1-chloro > 1-bromo > 1-iodo. This specific activity was not lowered in the nitroreductase deficient strain TA98NR and O-acety... |
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The reaction of poly-L-ornithine with 1-halo-2,4-dinitrobenzenes.
Int. J. Biochem. 13(4) , 513-6, (1981)
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Glutathione and mercapturic acid conjugations in the metabolism of 2,4-dinitrobromobenzene.
Drug Chem. Toxicol. 3(3) , 305-18, (1980) The formation of glutathione (GSH) conjugate in the detoxification of [Ring-UL-14C]-2,4-dinitrobromobenzene (DNBB) was investigated using rat liver cytosolic fraction. The mercapturic acid conjugate in rats was also studied by collection of urine of rats dose... |
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Nucleophilic radical aromatic substituion with superoxide ion. Frimer A and Rosenthal I.
Tetrahedron Lett. 17(32) , 2809-12, (1976)
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