Palmitoleic acid

Palmitoleic acid Structure
Palmitoleic acid structure
Common Name Palmitoleic acid
CAS Number 373-49-9 Molecular Weight 254.408
Density 0.9±0.1 g/cm3 Boiling Point 363.6±0.0 °C at 760 mmHg
Molecular Formula C16H30O2 Melting Point 0.5 °C
MSDS Chinese USA Flash Point 239.2±14.4 °C
Symbol GHS07
GHS07
Signal Word Warning

Induction of Hepatic and Endothelial Differentiation by Perfusion in a Three-Dimensional Cell Culture Model of Human Fetal Liver.

Tissue Eng. Part C Methods 21 , 705-15, (2015)

The development of functional engineered tissue constructs depends on high cell densities and appropriate vascularization. In this study we implemented a four-compartment three-dimensional perfusion bioreactor culture model for studying the effects of medium ...

Genetic obesity alters recruitment of TANK-binding kinase 1 and AKT into hypothalamic lipid rafts domains.

Neurochem. Int. 80 , 23-32, (2015)

Lipid rafts (LRs) are membrane subdomains enriched in cholesterol, glycosphingolipids and sphingolipids containing saturated fatty acid. Signaling proteins become concentrated in these microdomains mainly by saturated fatty acid modification, thus facilitatin...

Determination of free fatty acids in human serum by HPLC with fluorescence detection.

J. Chromatogr. Sci. 53 , 537-41, (2015)

It has been suggested that serum concentrations of polyunsaturated essential fatty acids correlate with the symptoms or severity of various diseases, including depression and Alzheimer-type dementia, and that determination of serum fatty acids might be import...

Palmitoleic acid (n-7) increases white adipocyte lipolysis and lipase content in a PPARα-dependent manner.

Am. J. Physiol. Endocrinol. Metab. 305(9) , E1093-102, (2013)

We investigated whether palmitoleic acid, a fatty acid that enhances whole body glucose disposal and suppresses hepatic steatosis, modulates triacylglycerol (TAG) metabolism in adipocytes. For this, both differentiated 3T3-L1 cells treated with either palmito...

Regulation of mitochondrial ceramide distribution by members of the BCL-2 family.

J. Lipid Res. 56 , 1501-10, (2015)

Apoptosis is an intricately regulated cellular process that proceeds through different cell type- and signal-dependent pathways. In the mitochondrial apoptotic program, mitochondrial outer membrane permeabilization by BCL-2 proteins leads to the release of ap...

Development and application of a comparative fatty acid analysis method to investigate voriconazole-induced hepatotoxicity.

Clin. Chim. Acta 438 , 126-34, (2014)

As fatty acids play an important role in biological regulation, the profiling of fatty acid expression has been used to discover various disease markers and to understand disease mechanisms. This study developed an effective and accurate comparative fatty aci...

Palmitoleic acid is elevated in fatty liver disease and reflects hepatic lipogenesis.

Am. J. Clin. Nutr. 101(1) , 34-43, (2015)

Biochemical evidence has linked the coordinate control of fatty acid (FA) synthesis with the activity of stearoyl-CoA desaturase-1 (SCD1). The ratio of 16:1n-7 to 16:0 [SCD1₁₆] in plasma triacylglycerol FA has been used as an index to reflect liver SCD1₁₆ act...

Serum unsaturated free Fatty acids: potential biomarkers for early detection and disease progression monitoring of non-small cell lung cancer.

J. Cancer 5(8) , 706-14, (2014)

Lung cancer (LC) is the deadliest cancer, with earlier stage patients having a better opportunity of long-term survival. The goal of this study is to screen less-invasive and efficient biomarkers for early detection of non-small cell LC (NSCLC).We performed t...

Decreased serum levels of free fatty acids are associated with breast cancer.

Clin. Chim. Acta 437 , 31-7, (2014)

Changes in the levels of lipids are associated with breast cancer (BC).Disease-specific serum free fatty acids (FFAs) were quantified using chip-based direct-infusion nanoelectrospray ionization-Fourier transform ion cyclotron resonance mass spectrometry (CBD...

Pu-erh tea down-regulates sterol regulatory element-binding protein and stearyol-CoA desaturase to reduce fat storage in Caenorhaditis elegans.

PLoS ONE 10(2) , e0113815, (2015)

Consumption of Pu-erh has been reported to result in numerous health benefits, but the mechanisms underlying purported weight-loss and lowering of lipid are poorly understood. Here, we used the nematode Caenorhaditis elegans to explore the water extract of Pu...