1-(chloromethyl)-2-isocyanatobenzene

1-(chloromethyl)-2-isocyanatobenzene Structure
1-(chloromethyl)-2-isocyanatobenzene structure
Common Name 1-(chloromethyl)-2-isocyanatobenzene
CAS Number 52986-66-0 Molecular Weight 167.59200
Density 1.241 Boiling Point 45ºC (0.2 torr)
Molecular Formula C8H6ClNO Melting Point N/A
MSDS Chinese USA Flash Point >230 °F
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Substituted 2-methylene-1,3-oxazolidines, -1,3-thiazolidines, -1,3-benzothiazines, -1,3-oxazines, and substituted imidazopyrimidinediones from Cl(CH2)nNCO and Cl(CH2)nNCS and active methylene compounds.

J. Org. Chem. 71(26) , 9743-50, (2006)

The reaction of omega-chloroalkyl isocyanates Cl(CH2)nNCO (n = 2 (2), 3 (4)) and isothiocyanate Cl(CH2)2NCS (3) with active methylene compounds CH2YY' 1 in the presence of Et3N or Na give 2-YY'-methylene-1,3-oxazolidines, (E,Z)-1,3-thiazolidines, and 1,3-oxaz...