4-mercaptophenylacetic acid
4-mercaptophenylacetic acid structure
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Common Name | 4-mercaptophenylacetic acid | ||
|---|---|---|---|---|
| CAS Number | 39161-84-7 | Molecular Weight | 168.21300 | |
| Density | 1.299g/cm3 | Boiling Point | 336ºC at 760mmHg | |
| Molecular Formula | C8H8O2S | Melting Point | 105-109ºC(lit.) | |
| MSDS | USA | Flash Point | 157ºC | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines.
Biopolymers 104 , 116-27, (2015) The cancer protein NY-ESO-1 has been shown to be one of the most promising vaccine candidates although little is known about its cellular function. Using a chemical protein strategy, the 180 amino acid polypeptide, tagged with an arginine solubilizing tail, w... |
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Flexible antibodies with nonprotein hinges.
Proc. Jpn. Acad.,. Ser. B, Phys. Biol. Sci. 87 , 603-16, (2011) There is a significant need for antibodies that can bind targets with greater affinity. Here we describe a novel strategy employing chemical semisynthesis to produce symmetroadhesins: antibody-like molecules having nonprotein hinge regions that are more flexi... |
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Cyclisation increases the stability of the sea anemone peptide APETx2 but decreases its activity at acid-sensing ion channel 3.
Mar. Drugs 10 , 1511-27, (2012) APETx2 is a peptide isolated from the sea anemone Anthopleura elegantissima. It is the most potent and selective inhibitor of acid-sensing ion channel 3 (ASIC3) and it is currently in preclinical studies as a novel analgesic for the treatment of chronic infla... |