4-Bromonaphthalen-1-ol

4-Bromonaphthalen-1-ol Structure
4-Bromonaphthalen-1-ol structure
Common Name 4-Bromonaphthalen-1-ol
CAS Number 571-57-3 Molecular Weight 223.066
Density 1.6±0.1 g/cm3 Boiling Point 346.4±15.0 °C at 760 mmHg
Molecular Formula C10H7BrO Melting Point 128-133°C
MSDS Chinese USA Flash Point 163.3±20.4 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Enantioselective synthesis of (+)-estrone exploiting a hydrogen bond-promoted Diels-Alder reaction.

J. Org. Chem. 75 , 2718-2721, (2010)

Starting from Dane's diene and methylcyclopentenedione, (+)-estrone is synthesized along the Quinkert-Dane route in 24% total yield. The key step is an enantioselective Diels-Alder reaction promoted by an amidinium catalyst as efficiently as by a traditional ...