2-Methylquinoxaline

2-Methylquinoxaline Structure
2-Methylquinoxaline structure
Common Name 2-Methylquinoxaline
CAS Number 7251-61-8 Molecular Weight 144.173
Density 1.1±0.1 g/cm3 Boiling Point 243.9±20.0 °C at 760 mmHg
Molecular Formula C9H8N2 Melting Point N/A
MSDS Chinese USA Flash Point 107.2±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Inhibitory effect of herbal medicines and their trapping abilities against methylglyoxal-derived advanced glycation end-products.

BMC Complement Altern. Med. 15 , 394, (2015)

Methylglyoxal (MG) is one of the most reactive glycating agents, which result the formation of advanced glycation end-products (AGEs) that have been implicated in the progression of age-related diseases. Inhibition of MG-induced AGE formation is the imperativ...

2-(3-Aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides: a novel cluster of tumor-specific cytotoxins which reverse multidrug resistance.

Bioorg. Med. Chem. 17 , 3909-15, (2009)

A series of 2-(3-aryl-2-propenoyl)-3-methylquinoxaline-1,4-dioxides 3a-l were prepared by condensation of various aryl aldehydes with 2-acetyl-3-methylquinoxaline-1,4-dioxide 2. These compounds inhibit the growth of human Molt 4/C8 and CEM T-lymphocytes and t...

Determination of methylglyoxal as 2-methylquinoxaline by high-performance liquid chromatography and its application to biological samples.

J. Chromatogr. A. 414(1) , 149-55, (1987)

Evidence of high levels of methylglyoxal in cultured Chinese hamster ovary cells.

Proc. Natl. Acad. Sci. U. S. A. 95(10) , 5533-8, (1998)

Methylglyoxal is an alpha-ketoaldehyde and dicarbonyl formed in cells as a side product of normal metabolism. Endogenously produced dicarbonyls, such as methylglyoxal, are involved in numerous pathogenic processes in vivo, including carcinogenesis and advance...

Methylglyoxal assay in cells as 2-methylquinoxaline using 1,2-diaminobenzene as derivatizing reagent.

Anal. Biochem. 234(2) , 221-4, (1996)