4-Amino-3-hydroxybenzoic acid

4-Amino-3-hydroxybenzoic acid Structure
4-Amino-3-hydroxybenzoic acid structure
Common Name 4-Amino-3-hydroxybenzoic acid
CAS Number 2374-03-0 Molecular Weight 153.14
Density 1.5±0.1 g/cm3 Boiling Point 385.7±37.0 °C at 760 mmHg
Molecular Formula C7H7NO3 Melting Point 211-215 °C(lit.)
MSDS Chinese USA Flash Point 187.1±26.5 °C
Symbol GHS07
GHS07
Signal Word Warning

3D-QSAR and molecular docking studies of benzaldehyde thiosemicarbazone, benzaldehyde, benzoic acid, and their derivatives as phenoloxidase inhibitors.

Bioorg. Med. Chem. 15 , 2006-15, (2007)

Phenoloxidase (PO), also known as tyrosinase, is a key enzyme in insect development, responsible for catalyzing the hydroxylation of tyrosine into o-diphenols and the oxidation of o-diphenols into o-quinones. Inhibition of PO may provide a basis for novel env...

Deconstructing fragment-based inhibitor discovery.

Nat. Chem. Biol. 2 , 720-3, (2006)

Fragment-based screens test multiple low-molecular weight molecules for binding to a target. Fragments often bind with low affinities but typically have better ligand efficiencies (DeltaG(bind)/heavy atom count) than traditional screening hits. This efficienc...