25-Hydroxycalciferol
25-Hydroxycalciferol structure
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Common Name | 25-Hydroxycalciferol | ||
|---|---|---|---|---|
| CAS Number | 21343-40-8 | Molecular Weight | 412.648 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 542.3±38.0 °C at 760 mmHg | |
| Molecular Formula | C28H44O2 | Melting Point | 45-51ºC | |
| MSDS | Chinese USA | Flash Point | 225.9±21.4 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Improved analysis of vitamin D metabolites in plasma using liquid chromatography tandem mass spectrometry, and its application to cardiovascular research.
Biomed. Chromatogr. 28(6) , 913-7, (2014) The accurate and specific measurement of vitamin D is increasingly important for determining the role of vitamin D in the pathogenesis of disease. Liquid chromatography coupled to tandem mass spectrometry (LC/MS/MS) has increasingly become the analytical moda... |
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Common variants in CYP2R1 and GC genes are both determinants of serum 25-hydroxyvitamin D concentrations after UVB irradiation and after consumption of vitamin D₃-fortified bread and milk during winter in Denmark.
Am. J. Clin. Nutr. 101(1) , 218-27, (2015) Little is known about how the genetic variation in vitamin D modulating genes influences ultraviolet (UV)B-induced 25-hydroxyvitamin D [25(OH)D] concentrations. In the Food with vitamin D (VitmaD) study, we showed that common genetic variants rs10741657 and r... |
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Prospective association of 25-hydroxyvitamin d3 and d2 with childhood lung function, asthma, wheezing, and flexural dermatitis.
Epidemiology 24(2) , 310-9, (2013) Higher serum total 25-hydroxyvitamin D (25(OH)D) concentrations have been associated with better lung function and lower risk of allergic disease. 25(OH)D3 constitutes the majority of total 25(OH)D and has been suggested to be more potent than 25(OH)D2. We st... |
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The 3 epimer of 25-hydroxycholecalciferol is present in the circulation of the majority of adults in a nationally representative sample and has endogenous origins.
J. Nutr. 144(7) , 1050-7, (2014) Fundamental knowledge gaps in relation to the 3 epimer of 25-hydroxycholecalciferol [3-epi-25(OH)D₃] limit our understanding of its relevance for vitamin D nutrition and health. The aims of this study were to characterize the 3-epi-25(OH)D₃ concentrations in ... |
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Prevalence and consequences of vitamin D insufficiency in women with takotsubo cardiomyopathy.
J. Clin. Endocrinol. Metab. 98(5) , E872-6, (2013) The purpose of this study was to identify the prevalence and clinical consequences of vitamin D insufficiency in patients with takotsubo cardiomyopathy.Takotsubo cardiomyopathy is a syndrome of acute, transient left ventricular dysfunction seen predominantly ... |
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Hypovitaminosis D in a sunny country: time trends, predictors, and implications for practice guidelines.
Metab. Clin. Exp. 63(7) , 968-78, (2014) The aim of the current study is to investigate the prevalence of hypovitaminosis D in Lebanese subjects, its robust predictors, evaluate the relationship between 25 hydroxy vitamin D [25(OH)D] and parathyroid hormone levels, and derive desirable vitamin D lev... |
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UV-dependent production of 25-hydroxyvitamin D2 in the recombinant yeast cells expressing human CYP2R1
Biochem. Biophys. Res. Commun. 434(2) , 311-5, (2013) • We produce 25-hydroxyvitamin D in the recombinant yeast expressing human CYP2R1. • Vitamin D2 is produced in yeast from endogenous ergosterol with UV irradiation. • We produce 25-hydroxyvitamin D2 in the recombinant yeast without added substrate. |
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The effect of obesity on the relationship between serum parathyroid hormone and 25-hydroxyvitamin D in women.
J. Clin. Endocrinol. Metab. 98(5) , E886-90, (2013) Obesity is associated with lower serum concentrations of 25-hydroxyvitamin D (25OHD) and higher intact PTH. The threshold of 25OHD needed to maximally suppress intact PTH has been suggested as a marker of optimal vitamin D status.In this study, we hypothesize... |
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The recognition of 25-hydroxyvitamin D2 and D3 by a new binding protein based 25-hydroxyvitamin D assay.
Clin. Chim. Acta 417 , 62-6, (2013) The circulating form of vitamin D, 25-Hydroxyvitamin D (25-OHD), is commonly measured in clinical labs to evaluate vitamin D status of an individual. Vitamin D exists in 2 major forms: vitamin D3 and D2. Current methodologies for 25-OHD testing include antibo... |
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The relationship between vitamin D status and adrenal insufficiency in critically ill children.
J. Clin. Endocrinol. Metab. 98(5) , E877-81, (2013) Recent studies in critically ill populations have suggested both adrenal insufficiency (AI) and vitamin D deficiency to be associated with worse clinical outcome. There are multiple mechanisms through which these pleiotropic hormones might synergistically inf... |