HC-030031
HC-030031 structure
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Common Name | HC-030031 | ||
|---|---|---|---|---|
| CAS Number | 349085-38-7 | Molecular Weight | 355.391 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C18H21N5O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Adjuvant Effect of an Alternative Plasticizer, Diisopropyl Adipate, on a Contact Hypersensitivity Mouse Model: Link with Sensory Ion Channel TRPA1 Activation.
Biol. Pharm. Bull. 38 , 1054-62, (2015) Due to health concerns about phthalate esters, the use of alternative plasticizers is being considered. Phthalate esters enhance skin sensitization to fluorescein isothiocyanate (FITC) in mouse models. We have demonstrated that phthalate esters stimulate tran... |
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Role of transient receptor potential and pannexin channels in cigarette smoke-triggered ATP release in the lung.
Thorax 69(12) , 1080-9, (2014) COPD is an inflammatory disease usually associated with cigarette smoking (CS) with an increasing global prevalence and no effective medication. Extracellular ATP is increased in the COPD affected lung and may play a key role in driving CS-induced airway infl... |
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Effects of methylglyoxal on human cardiac fibroblast: roles of transient receptor potential ankyrin 1 (TRPA1) channels.
Am. J. Physiol. Heart Circ. Physiol. 307(9) , H1339-52, (2014) Cardiac fibroblasts contribute to the pathogenesis of cardiac remodeling. Methylglyoxal (MG) is an endogenous carbonyl compound produced under hyperglycemic conditions, which may play a role in the development of pathophysiological conditions including diabet... |
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Smooth muscle-depressant activity of AP-18, a putative TRPA1 antagonist in the guinea pig intestine.
Pharmacology 94(3-4) , 131-4, (2014) AP-18, a putative antagonist at TRPA1 receptor/ion channel, caused smooth muscle relaxation at 10-100 µmol/l. It inhibited cholinergic twitch responses evoked by electrical field stimulation of cholinergic nerves as well as contractions in response to acetylc... |