Lupeol
Lupeol structure
|
Common Name | Lupeol | ||
|---|---|---|---|---|
| CAS Number | 545-47-1 | Molecular Weight | 426.717 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 488.1±14.0 °C at 760 mmHg | |
| Molecular Formula | C30H50O | Melting Point | 215-216ºC | |
| MSDS | Chinese USA | Flash Point | 216.9±12.4 °C | |
|
Analysis of triterpenoids and phytosterols in vegetables by thin-layer chromatography coupled to tandem mass spectrometry.
J. Chromatogr. A. 1381 , 229-38, (2015) Three TLC methods were used for an initial screening of some common plant triterpenoids and phytosterols in cuticular wax extracts of different vegetables (zucchini, eggplant, tomato, red pepper, mangold, spinach, lettuce, white-colored radicchio di Castelfra... |
|
|
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Bioorg. Med. Chem. 18 , 2225-31, (2010) There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one parasite species. Consequently, predicting the probability wi... |
|
|
Negative regulation of signal transducer and activator of transcription-3 signalling cascade by lupeol inhibits growth and induces apoptosis in hepatocellular carcinoma cells.
Br. J. Cancer 111(7) , 1327-37, (2014) Constitutive activation of signal transducer and activator of transcription signalling 3 (STAT3) has been linked with survival, proliferation and angiogenesis in a wide variety of malignancies including hepatocellular carcinoma (HCC).We evaluated the effect o... |
|
|
Lupeol inhibits proliferation and induces apoptosis of human pancreatic cancer PCNA-1 cells through AKT/ERK pathways.
Naunyn Schmiedebergs Arch. Pharmacol. 388(3) , 295-304, (2015) Lupeol, a dietary triterpene, present in many fruits and medicinal plants, has been reported to possess many pharmacological properties including anti-cancer activities both in vitro and in vivo. However, the precise mechanism involved remains largely unknown... |
|
|
Changes in the triterpenoid content of cuticular waxes during fruit ripening of eight grape (Vitis vinifera) cultivars grown in the Upper Rhine Valley.
J. Agric. Food Chem. 62(32) , 7998-8007, (2014) Triterpenoids present in grape cuticular waxes are of interest due to their potential role in protection against biotic stresses, their impact on the mechanical toughness of the fruit surface, and the potential industrial application of these biologically act... |
|
|
Effects of natural nuclear factor-kappa B inhibitors on anticancer drug efflux transporter human P-glycoprotein.
Biomed. Pharmacother. 70 , 140-5, (2015) Drug efflux transporter P-glycoprotein plays an important role in cancer chemotherapy. The nuclear factor-κB (NF-κB) transcription factors play critical roles in development and progression of cancer. In this study, the effects of natural compounds that can i... |
|
|
Hawthorn ethanolic extracts with triterpenoids and flavonoids exert hepatoprotective effects and suppress the hypercholesterolemia-induced oxidative stress in rats.
Iran. J. Basic Med. Sci. 18 , 691-9, (2015) The current study was aimed to determine the bioactive constituents and biological effects of the Crataegus monogyna ethanolic extracts from bark, leaves and berries on hypercholesterolemia.Oleanolic acid, ursolic acid, quercetin and lupeol concentrations wer... |
|
|
Mycobacterium tuberculosis and cholinesterase inhibitors from Voacanga globosa.
Eur. J. Med. Chem. 46 , 3118-23, (2011) Globospiramine (1), a new spirobisindole alkaloid possessing an Aspidosperma-Aspidosperma skeleton, together with deoxyvobtusine (2), deoxyvobtusine lactone (3), vobtusine lactone (4) and lupeol (5), were isolated and identified from Voacanga globosa through ... |
|
|
Scuteflorins A and B, dihydropyranocoumarins from Scutellaria lateriflora.
J. Nat. Prod. 72 , 983-7, (2009) Two new dihydropyranocoumarins, scuteflorins A (1) and B (2), together with the known compounds decursin (3), chrysin (4), oroxylin A (5), wogonin (6), 5,7-dihydroxy-8,2'-dimethoxyflavone, dihydrochrysin, dihydrooroxylin A, lupenol, scutellaric acid, pomolic ... |
|
|
alpha-Glucosidase inhibitory activity of triterpenoids from Cichorium intybus.
J. Nat. Prod. 71 , 910-3, (2008) Two new triterpenoids, 18alpha,19beta-20(30)-taraxasten-3beta,21alpha-diol (cichoridiol) (1) and 17-epi-methyl-6-hydroxyangolensate (intybusoloid) (2), were obtained from the methanolic extract of seeds of Cichorium intybus along with 11 known compounds, lupe... |