6-Chloro-1H-indole

6-Chloro-1H-indole Structure
6-Chloro-1H-indole structure
Common Name 6-Chloro-1H-indole
CAS Number 17422-33-2 Molecular Weight 151.59
Density 1.3±0.1 g/cm3 Boiling Point 293.0±13.0 °C at 760 mmHg
Molecular Formula C8H6ClN Melting Point 87-90 °C(lit.)
MSDS Chinese USA Flash Point 158.9±5.4 °C

Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs.

J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014)

Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional...

Toward prediction of alkane/water partition coefficients.

J. Med. Chem. 51 , 3720-30, (2008)

Partition coefficients were measured for 47 compounds in the hexadecane/water ( P hxd) and 1-octanol/water ( P oct) systems. Some types of hydrogen bond acceptor presented by these compounds to the partitioning systems are not well represented in the literatu...

Production of substituted L-tryptophans by fermentation.

Appl. Microbiol. 21(5) , 841-3, (1971)

Claviceps purpurea has been shown to produce extracellular l-tryptophan from indole in stirred fermentors. The substrate specificity of this conversion was investigated by using substituted indoles, anthranilic acid, and 4-chloro-anthranilic acid. Addition of...