Isobutylene Oxide
Isobutylene Oxide structure
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Common Name | Isobutylene Oxide | ||
|---|---|---|---|---|
| CAS Number | 558-30-5 | Molecular Weight | 72.10570 | |
| Density | 0.812 g/mL at 25 °C(lit.) | Boiling Point | 50-51 °C(lit.) | |
| Molecular Formula | C4H8O | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 33 °F | |
| Symbol |
GHS02, GHS05, GHS07 |
Signal Word | Danger | |
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Mutagenicity of 2-methylpropene (isobutene) and its epoxide in a modified Salmonella assay for volatile compounds.
Mutat. Res. 271(3) , 213-21, (1992) The mutagenic properties of 2-methylpropene (MP) and 2-methyl-1,2- epoxypropane (MEP) were investigated in the Salmonella assay. A simple exposure system, consisting of gastight tissue culture flasks, was used. This method has the advantage that the volatile ... |
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Comparative mutagenicity of 2-methylpropene (isobutene), its epoxide 2-methyl-1,2-epoxypropane and propylene oxide in the in vitro micronucleus test using human lymphocytes.
Mutagenesis 10(2) , 101-4, (1995) 2-Methylpropene (isobutene), a gaseous compound widely used in chemical industries, is metabolized to the epoxide 2-methyl-1,2-epoxypropane. The parent compound has previously been shown to be non-mutagenic in a modified Ames test, whereas the epoxide metabol... |
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In vitro biotransformation of 2-methylpropene (isobutene): epoxide formation in mice liver.
Arch. Toxicol. 65(4) , 263-7, (1991) Until now, no data are available concerning the biotransformation and toxicity of 2-methylpropene (or isobutene), a gaseous alkene widely used in industry (rubber, fuel additives, plastic polymers, adhesives, antioxidants). In this work, the biotransformation... |
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Metabolism and toxicity of 2-methylpropene (isobutene)--a review.
Crit. Rev. Toxicol. 27(3) , 223-32, (1997) 2-Methylpropene (MP) or isobutene is a gaseous chemical used on a large scale in the synthetic rubber industry. The present review covers the rather scarce literature on MP with respect to its metabolic fate and toxicity in laboratory animals and humans. It h... |
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Species-dependent differences in biotransformation pathways of 2-methylpropene (isobutene).
Chem. Res. Toxicol. 8(7) , 987-92, (1995) The biotransformation of 2-methylpropene, a gaseous alkene widely used in industry, was investigated in vitro in liver tissue of rats, mice, and humans. Interspecies comparison revealed that the lowest levels of the primary epoxide metabolite were detected in... |
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Protonated 2-methyl-1,2-epoxypropane: a challenging problem for density functional theory.
J. Org. Chem. 71(4) , 1592-7, (2006) Protonated epoxides feature prominently in organic chemistry as reactive intermediates. Herein, we describe 10 protonated epoxides using B3LYP, MP2, and CCSD/6-311++G calculations. Relative to CCSD, B3LYP consistently overestimates the C2-O bond length. Proto... |