4-(Trifluoromethyl)benzonitrile

4-(Trifluoromethyl)benzonitrile Structure
4-(Trifluoromethyl)benzonitrile structure
Common Name 4-(Trifluoromethyl)benzonitrile
CAS Number 455-18-5 Molecular Weight 171.119
Density 1.3±0.1 g/cm3 Boiling Point 183.2±0.0 °C at 760 mmHg
Molecular Formula C8H4F3N Melting Point 39-41 °C(lit.)
MSDS Chinese USA Flash Point 71.7±0.0 °C
Symbol GHS02 GHS07
GHS02, GHS07
Signal Word Danger

Nickel-catalyzed carbocyanation of alkynes with allyl cyanides.

J. Am. Chem. Soc. 131 , 10964, (2009)

Allyl cyanides are found to add across alkynes in the presence of a nickel/P(4-CF(3)-C(6)H(4))(3) catalyst to give polysubstituted 2,5-hexadienenitriles with defined stereo- and regiochemistry. Use of AlMe(2)Cl or AlMe(3) as a Lewis acid cocatalyst accelerate...

Improving palladium-catalyzed cyanation of aryl halides: development of a state-of-the-art methodology using potassium hexacyanoferrate (II) as cyanating agent. Schareina T, et al.

J. Organomet. Chem. 689(24) , 4576-83, (2004)