RICININE
RICININE structure
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Common Name | RICININE | ||
|---|---|---|---|---|
| CAS Number | 524-40-3 | Molecular Weight | 164.16 | |
| Density | 1.23 g/cm3 | Boiling Point | 370.9ºC at 760 mmHg | |
| Molecular Formula | C8H8N2O2 | Melting Point | 200-201ºC | |
| MSDS | Chinese USA | Flash Point | 178.1ºC | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Screening approach by ultra-high performance liquid chromatography-tandem mass spectrometry for the blood quantification of thirty-four toxic principles of plant origin. Application to forensic toxicology.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 975 , 65-76, (2014) Plant poisonings have left their mark on history and still cause many deaths, whether intentional or accidental. The means to show toxicological evidence of such poisonings should be implemented with great care. This article presents a technique for measuring... |
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Neutralising antibodies against ricin toxin.
PLoS ONE 6 , e20166, (2011) The Centers for Disease Control and Prevention have listed the potential bioweapon ricin as a Category B Agent. Ricin is a so-called A/B toxin produced by plants and is one of the deadliest molecules known. It is easy to prepare and no curative treatment is a... |
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Activity of Ricinus communis (Euphorbiaceae) and ricinine against the leaf-cutting ant Atta sexdens rubropilosa (Hymenoptera: Formicidae) and the symbiotic fungus Leucoagaricus gongylophorus.
Pest Manag. Sci. 60(9) , 933-8, (2004) The focus of this study was the identification of compounds from plant extracts for use in crop protection. This paper reports on the toxic activity of fractions of leaf extracts of Ricinus communis L (Euphorbiaceae) and isolated active compounds in the leaf-... |
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Quantification of ricinine in rat and human urine: a biomarker for ricin exposure.
J. Anal. Toxicol. 29(3) , 149-55, (2005) Ricin is a toxalbumin derived from the castor bean plant, Ricinus communis. Ricinine is an alkaloid (3-cyano-4-methoxy-N-methyl-2-pyridone) that shares a common plant source with ricin, and its presence in urine infers ricin exposure. A new quantification met... |
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High-speed counter-current chromatographic isolation of ricinine, an insecticide from Ricinus communis.
J. Chromatogr. A. 1216(19) , 4290-4, (2009) The alkaloid ricinine, an insecticide for leaf-cutting ant (Atta sexdens rubropilosa), was obtained from Ricinus communis. A two-phase solvent system composed of CH(2)Cl(2)/EtOH/H(2)O (93:35:72, v/v/v) was used for high-speed counter-current chromatographic (... |
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A simple method for screening and quantification of ricinine in feed with HPLC and LC-MS.
J. Chromatogr. Sci. 47(7) , 585-8, (2009) A simple high-performance liquid chromatography (HPLC) and liquid chromatography-mass spectrometry (LC-MS) method for screening and quantification of ricinine in feeds is established for use in feed quality control. Ricinine is extracted from the sample with ... |
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Suicidal death after injection of a castor bean extract (Ricinus communis L.).
Forensic Sci. Int. 189(1-3) , e13-20, (2009) The castor bean plant (Ricinus communis L.) or wonder tree is cultivated in many countries as an ornamental annual plant in gardens. The highest concentration of the lectin ricin is present in the seeds and pods. Ricin is considered as one of the most toxic n... |
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Ricinus communis intoxications in human and veterinary medicine-a summary of real cases.
Toxins (Basel.) 3(10) , 1332-72, (2011) Accidental and intended Ricinus communis intoxications in humans and animals have been known for centuries but the causative agent remained elusive until 1888 when Stillmark attributed the toxicity to the lectin ricin. Ricinus communis is grown worldwide on a... |
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Pharmacological evaluation of ricinine, a central nervous system stimulant isolated from Ricinus communis.
Pharmacol. Biochem. Behav. 63(3) , 367-75, (1999) The extract of the pericarp of castor bean (Ricinus communis) showed some typical central nervous system stimulant effects when administered to mice. The animals became exophthalmic, presented tremors and clonic seizures and died a few minutes after receiving... |
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Forensic determination of ricin and the alkaloid marker ricinine from castor bean extracts.
J. Forensic Sci. 46(5) , 1033-42, (2001) Chlamydia trachomatis L2 invasively attacks lymphatic and subepithelial tissues of the genital tract during the formation of primary lesions. This subsequently results in lymphadenopathy, and suggests a greater propensity for systemic dissemination. However, ... |