3-Fluorobenzyl chloride
3-Fluorobenzyl chloride structure
|
Common Name | 3-Fluorobenzyl chloride | ||
|---|---|---|---|---|
| CAS Number | 456-42-8 | Molecular Weight | 144.574 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 173.3±15.0 °C at 760 mmHg | |
| Molecular Formula | C7H6ClF | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 58.9±0.0 °C | |
| Symbol |
GHS02, GHS05 |
Signal Word | Danger | |
|
Truncated structures used in search for new lead compounds and in a retrospective analysis of thienopyrimidine-based EGFR inhibitors.
Eur. J. Med. Chem. 94 , 175-94, (2015) An approach for optimization of epidermal growth factor receptor tyrosine kinase (EGFR-TK) inhibitors using truncated thienopyrimidine structures combined with enzymatic assay has been evaluated. This was done by synthesis and EGFR activity measurement of a s... |
|
|
Distributed Drug Discovery, Part 3: using D(3) methodology to synthesize analogs of an anti-melanoma compound.
J. Comb. Chem. 11(1) , 34-43, (2009) For the successful implementation of Distributed Drug Discovery (D(3)) (outlined in the accompanying Perspective), students, in the course of their educational laboratories, must be able to reproducibly make new, high quality, molecules with potential for bio... |
|
|
Distributed Drug Discovery, Part 2: global rehearsal of alkylating agents for the synthesis of resin-bound unnatural amino acids and virtual D(3) catalog construction.
J. Comb. Chem. 11 , 14-33, (2009) Distributed Drug Discovery (D(3)) proposes solving large drug discovery problems by breaking them into smaller units for processing at multiple sites. A key component of the synthetic and computational stages of D(3) is the global rehearsal of prospective rea... |