Ranatensin

Ranatensin Structure
Ranatensin structure
Common Name Ranatensin
CAS Number 29451-71-6 Molecular Weight 1281.48000
Density 1.326 g/cm3 Boiling Point 1790.5ºC at 760 mmHg
Molecular Formula C61H84N16O13S Melting Point N/A
MSDS Chinese USA Flash Point 1036.6ºC

Molecular biology of bombesin-like peptides. Comparison of cDNAs encoding human gastrin-releasing peptide, human neuromedin B, and amphibian ranatensin.

Ann. N. Y. Acad. Sci. 547 , 10-20, (1988)

Bombesin-related peptides induce calcium mobilization in a subset of human small cell lung cancer cell lines.

J. Biol. Chem. 262(34) , 16456-60, (1987)

To examine the biochemical basis for growth factor-induced responses in human lung cancer cells, we used the quin2 technique to study the effect of the amphibian peptide bombesin and its congeners including mammalian gastrin-releasing peptide (GRP) on the int...

Identification of the C-terminal amino acid amides by carboxypeptidase Y digestion and fast atom bombardment mass spectrometry.

Biochem. Mol. Biol. Int. 34(5) , 897-907, (1994)

The combination method of carboxypeptidase Y digestion and fast atom bombardment (FAB) mass spectrometry is described for the identification of C-terminal amino acid amides in peptides. Carboxypeptidase Y has amidase activity as well as exopeptidase activity ...

Presence of ranatensin-like and bombesin-like peptides in amphibian brains.

Regul. Pept. 3(1) , 1-13, (1982)

Antibodies specific for the carboxyl-terminal regions of bombesin and of ranatensin were used to study the tissue distribution of substances immunochemically similar to these two peptides in three amphibian species. Brain extracts of Rana catesbeiana, Rana pi...

Demonstration of a pontine-hippocampal projection containing a ranatensin-like peptide.

Neurosci. Lett. 53(1) , 109-14, (1985)

Previous studies have demonstrated a neuronal system containing an immunoreactive ranatensin-like peptide (irRT) in rat brain. The results of the present study describe the ascending projections of a prominent irRT cell group in the pons. A major pontine irRT...

Stimulatory effects of bombesin-like peptides on hypothalamic arcuate neurons in rat brain slices.

Brain Res. Bull. 35(3) , 241-6, (1994)

The effects of bombesin, gastrin-releasing peptide, neuromedin C, ranatensin, and neuromedin B on hypothalamic arcuate neurons were tested in this study using extracellular single-unit recording in fresh brain tissue slices. Adult ovariectomized Sprague-Dawle...

Stimulation of growth hormone and prolactin release from rat pituitary cell aggregates by bombesin- and ranatensin-like peptides is potentiated by estradiol, 5 alpha-dihydrotestosterone, and dexamethasone.

Endocrinology 126(5) , 2257-66, (1990)

The effect of the bombesin-like peptides, gastrin-releasing peptide (GRP) and neuromedin-C (NMC), and the ranatensin-like peptides, neuromedin-B (NMB), neuromedin-B30 (NMB30), and neuromedin-B32 (NMB32), on pituitary GH and PRL release was studied in perifuse...

Two distinct receptor subtypes for mammalian bombesin-like peptides.

Trends Neurosci. 14(12) , 524-8, (1991)

The mammalian bombesin-like peptides, gastrin-releasing peptide (GRP) and neuromedin B (NMB), are structurally related neuropeptides that elicit a wide spectrum of biological activities including regulation of smooth muscle contraction, stimulation of secreti...

Bombesin-induced desensitization of enzyme secretion in dispersed acini from guinea pig pancreas.

Am. J. Physiol. 238(3) , G213-8, (1980)

Incubating dispersed acini from guinea pig pancreas with bombesin and then washing the cells to remove bombesin reduced the subsequent stimulation of amylase secretion caused by bombesin, litorin, or ranatensin by as much as 80%, but did not alter the stimula...

Effects of neuromedins and related peptides on the body temperature of rats.

Jpn. J. Physiol. 45(1) , 37-45, (1995)

Neuromedin B (NMB) and neuromedin C (NMC) are peptides found in the mammalian central nervous system, and their concentrations are particularly high in the hypothalamus. The amino acid sequences of these peptides are similar to that of bombesin, which is know...