4-phenylbutan-2-amine
4-phenylbutan-2-amine structure
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Common Name | 4-phenylbutan-2-amine | ||
|---|---|---|---|---|
| CAS Number | 22374-89-6 | Molecular Weight | 149.233 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 221.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C10H15N | Melting Point | -50ºC | |
| MSDS | Chinese USA | Flash Point | 97.8±0.0 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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Quantification of Methylphenidate, Dexamphetamine, and Atomoxetine in Human Serum and Oral Fluid by HPLC With Fluorescence Detection.
Ther. Drug Monit. 38 , 98-107, (2016) For psychostimulants, a marked individual variability in the dose-response relationship and large differences in plasma concentrations after similar doses are known. Therefore, optimizing the efficacy of these drugs is at present the most promising way to exp... |
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Identification and quantitation of an oxidative metabolite of labetalol in sheep: pharmacokinetic and metabolic implications.
Biol. Mass Spectrom. 21(11) , 534-40, (1992) A sensitive and selective assay has been developed for the identification and quantitation of 3-amino-1-phenyl butane (3-APB), a metabolite of labetalol, in biological fluids using electron impact gas chromatography/mass-selective detection. Samples were extr... |
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Disposition, metabolism, and pharmacodynamics of labetalol in adult sheep.
Drug Metab. Dispos. 21(2) , 284-92, (1993) Labetalol causes significant maternal and fetal metabolic effects in pregnant sheep (Yeleswaram et al., J. Pharmacol. Exp. Ther. 262, 683-691 (1992)). This study was undertaken to investigate the contribution of skeletal muscles in the development of metaboli... |
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Labetalol is metabolized oxidatively in humans.
Res. Commun. Chem. Pathol. Pharmacol. 62(1) , 3-17, (1988) Previous studies on the metabolic fate of antihypertensive agent labetalol in humans identified only conjugated metabolites of the drug and accounted for only a portion of the dose. In this study, urine samples obtained from three patients on chronic labetalo... |
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Stereospecific gas chromatographic/mass spectrometric assay of the chiral labetalol metabolite 3-amino-1-phenylbutane.
Biol. Mass Spectrom. 20(12) , 751-8, (1991) We previously identified 3-amino-1-phenylbutane (APB) as an oxidative N-dealkylated, metabolite of the antihypertensive agent labetalol. Labetalol has two asymmetric centers and is used clinically as a mixture of the four possible stereoisomers; APB has one a... |
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A labetalol metabolite with analytical characteristics resembling amphetamines.
J. Anal. Toxicol. 19(2) , 84-6, (1995) A metabolite of labetalol that is responsible for previous reports of false-positive assays for amphetamines by thin-layer chromatography and immunoassay has been identified. The compound, 3-amino-1-phenylbutane (APB), an oxidative metabolite of labetalol, wa... |