α-Cyclodextrin
α-Cyclodextrin structure
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Common Name | α-Cyclodextrin | ||
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| CAS Number | 10016-20-3 | Molecular Weight | 972.844 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | 1410.8±60.0 °C at 760 mmHg | |
| Molecular Formula | C36H60O30 | Melting Point | 278ºC | |
| MSDS | Chinese USA | Flash Point | 807.1±32.9 °C | |
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Photoreversible polymer-surfactant micelles using the molecular recognition of α-cyclodextrin.
Langmuir 29(10) , 3188-94, (2013) Photoreversible micelles were achieved by a combination of commercially available components sodium alginate (Alg), tetradecyltrimethylammonium bromide (TTAB), α-cyclodextrin (α-CD), and 4-(phenylazo)benzoic acid (PBA). Under visible light irradiation, α-CD i... |
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An intelligent anticorrosion coating based on pH-responsive supramolecular nanocontainers.
Nanotechnology 23(50) , 505705, (2012) The hollow mesoporous silica nanoparticles (HMSNs), which have been used as the nanocontainers for the corrosion inhibitor, benzotriazole, were fabricated using the hard-template method. Alkaline-responsive HMSNs based on cucurbit[6]uril (CB[6])/bisammonium s... |
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Beads made of α-cyclodextrin and soybean oil: the drying method influences bead properties and drug release.
Drug Dev. Ind. Pharm. 39(9) , 1306-14, (2013) Freeze-dried beads made of α-cyclodextrin and soybean oil were reported previously as an efficient system for the oral delivery of lipophilic drugs. In the present study, oven-drying was evaluated as another method for drying beads. Oven-drying was optimised ... |
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Souroubea sympetala (Marcgraviaceae): a medicinal plant that exerts anxiolysis through interaction with the GABAA benzodiazepine receptor.
Can. J. Physiol. Pharmacol. 92(9) , 758-64, (2014) The mode of action of the anxiolytic medicinal plant Souroubea sympetala was investigated to test the hypothesis that extracts and the active principle act at the pharmacologically important GABAA-benzodiazepine (GABAA-BZD) receptor. Leaf extracts prepared by... |
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Expansion-contraction of photoresponsive artificial muscle regulated by host-guest interactions.
Nat. Commun. 3 , 1270, (2012) The development of stimulus-responsive polymeric materials is of great importance, especially for the development of remotely manipulated materials not in direct contact with an actuator. Here we design a photoresponsive supramolecular actuator by integrating... |
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Structure determination of fexofenadine-α-cyclodextrin complex by quantitative 2D ROESY analysis and molecular mechanics studies.
Magn. Reson. Chem. 50(4) , 299-304, (2012) Complexation of fexofenadine with α-cyclodextrin in aqueous medium was studied. The stoichiometry of the resulting inclusion complex was determined by (1) H NMR titration data. 2D ROESY data provided the evidence of formation of the complex by entry of the ph... |
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Possible enhancing mechanisms for gene transfer activity of glucuronylglucosyl-β-cyclodextrin/dendrimer conjugate.
Int. J. Pharm. 426(1-2) , 239-47, (2012) We previously reported that glucuronylglucosyl-β-cyclodextrin (GUG-β-CyD) conjugate with polyamidoamine starburst dendrimer (GUG-β-CDE conjugate) with the average degree of substitution (DS) of cyclodextrin (CyD) of 1.8 (GUG-β-CDE conjugate (DS 1.8)), showed ... |
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Systemic delivery of transthyretin siRNA mediated by lactosylated dendrimer/α-cyclodextrin conjugates into hepatocyte for familial amyloidotic polyneuropathy therapy.
Amyloid 19 Suppl 1 , 47-9, (2012) RNA interference (RNAi) is a sequence-specific gene-silencing mechanism triggered by double-stranded RNA and powerful tools for a gene function study and RNAi therapy. Although siRNAs offer several advantages as potential new drugs to treat various diseases, ... |
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Potential use of folate-polyethylene glycol (PEG)-appended dendrimer (G3) conjugate with α-cyclodextrin as DNA carriers to tumor cells.
Cancer Gene Ther. 19(5) , 358-66, (2012) We previously reported that polyamidoamine STARBURST dendrimer (generation 3, G3) (dendrimer) conjugate with α-cyclodextrin (α-CyD) having an average degree of substitution of 2.4 of α-CyD (α-CDE) provided remarkable aspects as novel carriers for DNA and smal... |
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α-Cyclodextrin dimer complexes of dopamine and levodopa derivatives to assess drug delivery to the central nervous system: ADME and molecular docking studies.
Int. J. Nanomedicine 7 , 3211-9, (2012) This paper attempts to predict and emphasize molecular interactions of dopamine, levodopa, and their derivatives (Dopimid compounds) containing 2-phenyl-imidazopyridine moiety with the α-cyclodextrin dimer in order to assess and improve drug delivery to the c... |