4-Phenoxyphenol

4-Phenoxyphenol Structure
4-Phenoxyphenol structure
Common Name 4-Phenoxyphenol
CAS Number 831-82-3 Molecular Weight 186.207
Density 1.2±0.1 g/cm3 Boiling Point 313.8±25.0 °C at 760 mmHg
Molecular Formula C12H10O2 Melting Point 80-84 °C(lit.)
MSDS Chinese USA Flash Point 141.4±17.4 °C

Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspase activity by 50% (I50) and utilized these data to develop ...

Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives.

Bioorg. Med. Chem. Lett. 18 , 6549-52, (2008)

The synthesis and biological evaluation of a series of diphenyl ether derivatives were described. The compounds can either activate or inhibit the aminopeptidase activity of leukotriene A(4) hydrolase, while at the same time do not influence the hydrolase act...