4-Phenoxyphenol

Modify Date: 2024-01-02 16:50:53

4-Phenoxyphenol Structure
4-Phenoxyphenol structure
Common Name 4-Phenoxyphenol
CAS Number 831-82-3 Molecular Weight 186.207
Density 1.2±0.1 g/cm3 Boiling Point 313.8±25.0 °C at 760 mmHg
Molecular Formula C12H10O2 Melting Point 80-84 °C(lit.)
MSDS Chinese USA Flash Point 141.4±17.4 °C

 Use of 4-Phenoxyphenol


BIF-44, also known as 4-Phenoxyphenol and Hydroquinone monophenyl ether, is a sensitizer of BCL-2-associated X protein (BAX) activation by binding to a pocket formed by the junction of the α3-α4 and α5-α6 hairpins. BIF-44 enhances BAX activity.

 Names

Name 4-phenoxyphenol
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.2±0.1 g/cm3
Boiling Point 313.8±25.0 °C at 760 mmHg
Melting Point 80-84 °C(lit.)
Molecular Formula C12H10O2
Molecular Weight 186.207
Flash Point 141.4±17.4 °C
Exact Mass 186.068085
PSA 29.46000
LogP 3.35
Vapour Pressure 0.0±0.7 mmHg at 25°C
Index of Refraction 1.605
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
Water Solubility insoluble

 Safety Information

Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi:Irritant
Risk Phrases R36/37/38
Safety Phrases S26-S36-S37/39
RIDADR NONH for all modes of transport
WGK Germany 3
Packaging Group I; II; III
HS Code 29095090

 Synthetic Route

 Customs

HS Code 2909500000
Summary 2909500000 ether-phenols, ether-alcohol-phenols and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%

 Articles2

More Articles
Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.

J. Med. Chem. 48 , 7234-42, (2005)

In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspas...

Activation and inhibition of leukotriene A4 hydrolase aminopeptidase activity by diphenyl ether and derivatives.

Bioorg. Med. Chem. Lett. 18 , 6549-52, (2008)

The synthesis and biological evaluation of a series of diphenyl ether derivatives were described. The compounds can either activate or inhibit the aminopeptidase activity of leukotriene A(4) hydrolase...

 Synonyms

4-Phenoxyphenol
o-Phenylhydroquinone
EINECS 212-611-1
MFCD00002331
Phenol, 4-phenoxy-
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