TRIFLUOROMETHANESULFONAMIDE

TRIFLUOROMETHANESULFONAMIDE Structure
TRIFLUOROMETHANESULFONAMIDE structure
Common Name TRIFLUOROMETHANESULFONAMIDE
CAS Number 421-85-2 Molecular Weight 149.09200
Density 1.73g/cm3 Boiling Point 164.6ºC at 760 mmHg
Molecular Formula CH2F3NO2S Melting Point 120-124 °C(lit.)
MSDS Chinese USA Flash Point 53.3ºC
Symbol GHS07
GHS07
Signal Word Warning

Intrinsic thermodynamics of ethoxzolamide inhibitor binding to human carbonic anhydrase XIII.

BMC Biophys. 5 , 12, (2013)

Human carbonic anhydrases (CAs) play crucial role in various physiological processes including carbon dioxide and hydrocarbon transport, acid homeostasis, biosynthetic reactions, and various pathological processes, especially tumor progression. Therefore, CAs...

Role of hepatic carbonic anhydrase in de novo lipogenesis.

Biochem. J. 310 ( Pt 1) , 197-202, (1995)

The role of carbonic anhydrase in de novo lipid synthesis was examined by measuring [1-14C]acetate incorporation into total lipids, fatty acids and non-saponifiable lipids in freshly isolated rat hepatocytes. Two carbonic anhydrase inhibitors, trifluoromethyl...

Synthesis of N-[2-(2,4-Difluorophenoxy)trifluoromethyl-3-pyridyl]sulfonamides and their inhibitory activities against secretory phospholipase A₂.

Chem. Pharm. Bull. 59(8) , 1069-72, (2011)

N-[2-(2,4-Difluorophenoxy)trifluoromethyl-3-pyridyl]sulfonamide derivatives 3-6 were prepared by the reaction of 3-pyridylamines and sulfonyl chlorides. Inhibitory activities of these compounds toward secretory phospholipase A₂ (sPLA₂) were examined and N-[2-...