Dimethyl sulfate

Dimethyl sulfate Structure
Dimethyl sulfate structure
Common Name Dimethyl sulfate
CAS Number 77-78-1 Molecular Weight 126.132
Density 1.3±0.1 g/cm3 Boiling Point 188.0±0.0 °C at 760 mmHg
Molecular Formula C2H6O4S Melting Point -32ºC
MSDS Chinese USA Flash Point 83.3±0.0 °C
Symbol GHS05 GHS06 GHS08
GHS05, GHS06, GHS08
Signal Word Danger

Molecularly imprinted polymers with synthetic dummy template for simultaneously selective removal and enrichment of ginkgolic acids from Ginkgo biloba L. leaves extracts.

J. Chromatogr. A. 1368 , 44-51, (2014)

Dummy molecularly imprinted polymers (DMIPs) for simultaneously selective removal and enrichment of ginkgolic acids (GAs) during the processing of Ginkgo biloba leaves have been prepared. Two dummy template molecule with similar structural skeleton to GAs, 6-...

Genome-wide profiling of in vivo RNA structure at single-nucleotide resolution using structure-seq.

Nat. Protoc. 10 , 1050-66, (2015)

Structure-seq is a high-throughput and quantitative method that provides genome-wide information on RNA structure at single-nucleotide resolution. Structure-seq can be performed both in vivo and in vitro to study RNA structure-function relationships, RNA regu...

Simultaneous quantification of trihalomethanes and haloacetic acids in cheese by on-line static headspace gas chromatography-mass spectrometry.

J. Chromatogr. A. 1408 , 22-9, (2015)

Trihalomethanes (THMs) and haloacetic acids (HAAs) are the two most prevalent classes of disinfection by-products (DBPs) that are present in treated water. Four THMs and six HAAs are regulated by several countries in drinking waters but no regulation for thes...

Novel Coumarin Substituted Water Soluble Cyclophosphazenes as "Turn-Off" Type Fluorescence Chemosensors for Detection of Fe(3+) ions in Aqueous Media.

J. Fluoresc. 25 , 1819-30, (2015)

In the present work, 3-[2-(diethylamino)ethyl]-7-oxy-4-methylcoumarin substituted cyclotriphosphazene (4) and cyclotetraphosphazene (5) derivatives were synthesized by the reactions of hexachlorocyclotriphosphazene (1) or octachlorocyclotetraphosphazene (2) w...

Synthesis and evaluation of chloramphenicol homodimers: molecular target, antimicrobial activity, and toxicity against human cells.

PLoS ONE 10 , e0134526, (2015)

As fight against antibiotic resistance must be strengthened, improving old drugs that have fallen in reduced clinical use because of toxic side effects and/or frequently reported resistance, like chloramphenicol (CAM), is of special interest. Chloramphenicol ...

[Research on determination of total volatile organic sulfur compounds in the atmosphere].

Huan Jing Ke Xue 32(12) , 3617-22, (2011)

A detection technology was established comprising trap, desorption, oxidation and UV fluorescence determination process, and used for the test of total concentration of trace volatile sulfur compounds (VSCs) in the atmosphere. A cryogenic trap-thermal desorpt...

The stability of DNA intrastrand cross-links of antitumor transplatin derivative containing non-bulky methylamine ligands.

J. Biol. Inorg. Chem. 19(7) , 1203-8, (2014)

Oligonucleotides modified by clinically ineffective trans-diamminedichloridoplatinum(II) (transplatin) have been shown to be effective modulators of gene expression. This is so because in some nucleotide sequences the 1,3-GNG intrastrand adducts formed by tra...

Assay at low ppm level of dimethyl sulfate in starting materials for API synthesis using derivatization in ionic liquid media and LC-MS.

J. Pharm. Biomed. Anal. 75 , 1-6, (2013)

Dimethyl sulfate (DMS) is frequently used in pharmaceutical manufacturing processes as an alkylating agent. Trace levels of DMS in drug substances should be carefully monitored since the compound can become an impurity which is genotoxic in nature. Derivatiza...

Analysis of haloacetic acids in water and air (aerosols) from indoor swimming pools using HS-SPME/GC/ECD.

J. Environ. Sci. Health. A. Tox. Hazard. Subst. Environ. Eng. 47(2) , 176-83, (2012)

A solid phase microextraction method was used for the analysis of nine haloacetic acids (HAAs) in water and air (aerosols) from indoor swimming pools (ISPs). The analysis is characterized by derivatization of HAAs to their methyl-esters with dimethyl sulphate...

Human AP endonuclease inefficiently removes abasic sites within G4 structures compared to duplex DNA.

Nucleic Acids Res. 42(12) , 7708-19, (2014)

Excision repair processes are essential to maintain genome stability. A decrease in efficiency and fidelity of these pathways at regions of the genome that can assume non-canonical DNA structures has been proposed as a possible mechanism to explain the increa...