CP-135807
CP-135807 structure
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Common Name | CP-135807 | ||
|---|---|---|---|---|
| CAS Number | 151272-90-1 | Molecular Weight | 351.40200 | |
| Density | 1.343g/cm3 | Boiling Point | 548.7ºC at 760 mmHg | |
| Molecular Formula | C19H21N5O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 285.6ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Combined administration of a 5-hydroxytryptamine (5-HT)1D antagonist and a 5-HT reuptake inhibitor synergistically increases 5-HT release in guinea pig hypothalamus in vivo.
J. Neurochem. 67(5) , 2204-7, (1996) In vivo microdialysis in guinea pig hypothalamus was used to study the effect of serotonin [5-hydroxytryptamine (5-HT)] subtype 1D autoreceptor blockade on the increase in extracellular 5-HT levels produced by a selective 5-HT reuptake inhibitor (SSRI). Admin... |
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In vitro characterization of AR-A000002, a novel 5-hydroxytryptamine(1B) autoreceptor antagonist.
Eur. J. Pharmacol. 499(1-2) , 67-75, (2004) The in vitro pharmacological properties of AR-A000002 ((R)-N-[5-methyl-8-(4-methylpiperazin-1-yl)-1,2,3,4-tetrahydro-2-naphthyl]-4-morpholinobenzamide), a novel 5-hydroxytryptamine (5-HT)(1B) receptor antagonist, were studied. AR-A000002 bound with high affin... |
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