chlorophenylsulfone
chlorophenylsulfone structure
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Common Name | chlorophenylsulfone | ||
|---|---|---|---|---|
| CAS Number | 98-09-9 | Molecular Weight | 176.621 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | 251.5±9.0 °C at 760 mmHg | |
| Molecular Formula | C6H5ClO2S | Melting Point | 14.5 °C | |
| MSDS | Chinese USA | Flash Point | 105.9±18.7 °C | |
| Symbol |
GHS05, GHS07, GHS08 |
Signal Word | Danger | |
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Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs.
J. Enzyme Inhib. Med. Chem. 29(6) , 846-67, (2014) Because of the pivotal role of cyclooxygenase (COX) in the inflammatory processes, non-steroidal anti-inflammatory drugs (NSAIDs) that suppress COX activities have been used clinically for the treatment of inflammatory diseases/syndromes; however, traditional... |
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Design, synthesis, and bioevaluation of paeonol derivatives as potential anti-HBV agents.
Eur. J. Med. Chem. 90 , 428-35, (2015) Hepatitis B virus (HBV) is a causative reagent that frequently causes progressive liver diseases, leading to the development of acute, chronic hepatitis, cirrhosis, and eventually hepatocellular carcinoma (HCC). Despite several antiviral drugs including inter... |
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Comparison of manual and benzenesulfonyl chloride-semiautomated thiochrome methods for determination of thiamine in foods.
J. Assoc. Off. Anal. Chem. 64(3) , 616-22, (1981) A semiautomated procedure was used to measure the fluorescence of sample extracts before and after the addition of benzenesulfonyl chloride (BSC). Addition of BSC inhibited thiochrome formation and provided a more representative blank based on the fluorescenc... |
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2,4-Dinitrobenzenesulfonyl fluoresceins as fluorescent alternatives to Ellman's reagent in thiol-quantification enzyme assays.
Angew. Chem. Int. Ed. Engl. 44(19) , 2922-5, (2005)
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Microsphere formation in a series of derivatized alpha-amino acids: properties, molecular modeling, and oral delivery of salmon calcitonin.
J. Med. Chem. 38(21) , 4257-62, (1995) A series of benzoylated and phenylsulfonylated amino acids are novel, low molecular weight, self-assembling molecules. At low pH, these compounds form microspheres that dissolve readily under neutral conditions. In a given synthetic series, those molecules wi... |
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Discovery of a β-glucosidase inhibitor from a chemically engineered extract prepared through sulfonylation.
Mol. Divers. 15(3) , 713-9, (2011) A semisynthetic β-glucosidase inhibitor was identified from a chemically engineered extract prepared by reaction with benzenesulfonyl chloride. The structure includes a natural histamine portion and a benzenesulfonyl portion introduced during the diversificat... |
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Determination of low molecular weight aliphatic primary amines in urine as their benzenesulphonyl derivatives by gas chromatography with flame photometric detection.
Biomed. Chromatogr. 6(5) , 251-4, (1992) A selective and sensitive method for the determination of low molecular weight aliphatic primary amines in urine is described. These amines were converted into their benzenesulphonyl derivatives by a modified Hinsberg procedure, and measured by gas chromatogr... |
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Substituted N-(3,5-dichlorobenzenesulfonyl)-L-prolyl-phenylalanine analogues as potent VLA-4 antagonists.
Bioorg. Med. Chem. Lett. 12(4) , 637-40, (2002) A series of substituted N-(3,5-dichlorobenzenesulfonyl)-L-prolyl- and alpha-methyl-L-prolyl-phenylalanine derivatives was prepared as VLA-4/VCAM antagonists. The compounds showed excellent potency with a wide variety of neutral, polar, electron withdrawing or... |
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Unusual reactions of magnesium indolates with benzenesulfonyl chloride. Wenkert E, et al.
J. Org. Chem. 52(15) , 3404-3409, (1987)
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Analysis of primary and secondary aliphatic amines in waste water and surface water by gas chromatography-mass spectrometry after derivatization with 2, 4-dinitrofluorobenzene or benzenesulfonyl chloride. Sacher F, et al.
J. Chromatogr. A. A764(1) , 85-93, (1997)
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