2-Chloro-1,1,1-Trimethoxyethane

2-Chloro-1,1,1-Trimethoxyethane Structure
2-Chloro-1,1,1-Trimethoxyethane structure
Common Name 2-Chloro-1,1,1-Trimethoxyethane
CAS Number 74974-54-2 Molecular Weight 154.592
Density 1.1±0.1 g/cm3 Boiling Point 143.2±35.0 °C at 760 mmHg
Molecular Formula C5H11ClO3 Melting Point N/A
MSDS Chinese USA Flash Point 40.8±26.0 °C
Symbol GHS02
GHS02
Signal Word Warning

New transient receptor potential vanilloid subfamily member 1 positron emission tomography radioligands: synthesis, radiolabeling, and preclinical evaluation.

ACS Chem. Neurosci. 4(4) , 624-34, (2013)

The transient receptor potential vanilloid subfamily member 1 (TRPV1) cation channel is known to be involved in pain nociception and neurogenic inflammation, and accumulating evidence suggests that it plays an important role in several central nervous system ...

CVT-4325: a potent fatty acid oxidation inhibitor with favorable oral bioavailability.

Bioorg. Med. Chem. Lett. 14 , 6017-6021, (2004)

New inhibitors of palmitoyl-CoA oxidation are based on the introduction of nitrogen heterocycles in the 'Western Portion' of the molecule. SAR studies led to the discovery of CVT-4325 (shown), a potent FOXi (IC50=380 nM rat mitochondria) with favorable PK pro...

A new synthesis of 1, 2, 4-triazolin-5-ones: application to the convergent synthesis of an NK 1 antagonist. Cowden CJ, et al.

Tetrahedron Lett. 41(44) , 8661-64, (2000)