Nipecotamide
Nipecotamide structure
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Common Name | Nipecotamide | ||
|---|---|---|---|---|
| CAS Number | 4138-26-5 | Molecular Weight | 128.172 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 311.7±31.0 °C at 760 mmHg | |
| Molecular Formula | C6H12N2O | Melting Point | 103-106 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 142.3±24.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Effects of sodium n-dipropylacetate, muscimol hydrobromide and (R,S) nipecotic acid amide on isolation-induced aggressive behavior in mice.
Psychopharmacology 70(3) , 287-90, (1980) An inhibitor of GABA-T (sodium n-dipropylacetate), a GABA agonist (muscimol hydrobromide) and an inhibitor of GABA uptake (R,S) nipecotic acid amide were administered to DBA/2 isolated aggressive mice throughout three successive daily experimental sessions. A... |
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Gabaergic modulation of mouse-killing in the rat.
Psychopharmacology 83(4) , 367-72, (1984) When GABA-potentiating compounds were administered IP to rats with prior experience of mouse-killing behaviour, a reduction of killing was observed with gamma-vinyl GABA (200 and 400 mg/kg) and nipecotic acid amide (400 mg/kg), while no significant effect was... |
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Relationships between the chemical constitution of carbamoylpiperidines and related compounds, and their inhibition of ADP-induced human blood platelet aggregation.
Thromb. Res. 22(5-6) , 665-80, (1981)
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Nipecotic and iso-nipecotic amides as potent and selective somatostatin subtype-2 receptor agonists.
Bioorg. Med. Chem. Lett. 11(3) , 415-7, (2001) N-Substituted nipecotic and iso-nipecotic amides of beta-methylTrpLys tert-butyl ester were found to be novel, selective and potent agonists of the somatostatin subtype-2 receptor in vitro. For example iso-nipecotic amide 8a showed high hsst2 binding affinity... |