5-Brom-2-fluorpyridin
5-Brom-2-fluorpyridin structure
|
Common Name | 5-Brom-2-fluorpyridin | ||
|---|---|---|---|---|
| CAS Number | 766-11-0 | Molecular Weight | 175.99 | |
| Density | 1.7±0.1 g/cm3 | Boiling Point | 178.0±20.0 °C at 760 mmHg | |
| Molecular Formula | C5H3BrFN | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 61.4±21.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Versatile synthesis of 3,5-disubstituted 2-fluoropyridines and 2-pyridones.
J. Org. Chem. 68(8) , 3352-5, (2003) 5-bromo-2-fluoro-3-pyridylboronic acid (3) was prepared in high yield by ortho-lithiation of 5-bromo-2-fluoropyridine (1), followed by reaction with trimethylborate. Suzuki reaction of 3 with a range of aryl iodides gave 3-monosubstituted 5-bromo-2-fluoropyri... |
|
|
Synthesis of two fluoro analogues of the nicotinic acetylcholine receptor agonist UB-165.
J. Org. Chem. 68(6) , 2475-8, (2003) Two racemic fluoropyridine analogues 4 and 5 of the potent nicotinic agonist UB-165 have been synthesized. Halogenated pyridines 7 and 12 provided the organometallic reagents needed for the Negishi and Suzuki coupling reactions used for the preparation of 4 a... |
|
|
Aromatic fluorine compounds. XI. Replacement of chlorine by fluorine in halopyridines. Finger GC, et al.
J. Org. Chem. 28(6) , 1666-1668, (1963)
|