1-Cyanocyclopropanecarboxylic acid

1-Cyanocyclopropanecarboxylic acid Structure
1-Cyanocyclopropanecarboxylic acid structure
Common Name 1-Cyanocyclopropanecarboxylic acid
CAS Number 6914-79-0 Molecular Weight 111.099
Density 1.4±0.1 g/cm3 Boiling Point 325.0±25.0 °C at 760 mmHg
Molecular Formula C5H5NO2 Melting Point 140 °C(lit.)
MSDS Chinese USA Flash Point 150.3±23.2 °C
Symbol GHS05 GHS07
GHS05, GHS07
Signal Word Danger

Development of amidine-based sphingosine kinase 1 nanomolar inhibitors and reduction of sphingosine 1-phosphate in human leukemia cells.

J. Med. Chem. 54(10) , 3524-48, (2011)

Sphingosine 1-phosphate (S1P) is a bioactive lipid that has been identified as an accelerant of cancer progression. The sphingosine kinases (SphKs) are the sole producers of S1P, and thus, SphK inhibitors may prove effective in cancer mitigation and chemosens...

Substituted cyclopropanes. 5. 1-Cyanocyclopropanecarboxylic acid. Jones PG and Schrumpf G.

Acta Crystallogr. C Struct. Chem. 43(8) , 1576-79, (1987)

Homoconjugate Addition of Nucleophiles to Cyclopropane-1, 1-Dicarboxylate Derivatives: 2-Oxo-1-Phenyl-3-Pyrrolidinecarboxylic Acid. Singh RK and Danishefsky S.

Organic Synth. , 66-66