1,3-Diaminopropan-2-ol

1,3-Diaminopropan-2-ol Structure
1,3-Diaminopropan-2-ol structure
Common Name 1,3-Diaminopropan-2-ol
CAS Number 616-29-5 Molecular Weight 90.124
Density 1.1±0.1 g/cm3 Boiling Point 236.6±20.0 °C at 760 mmHg
Molecular Formula C3H10N2O Melting Point 40-44 °C(lit.)
MSDS Chinese USA Flash Point 96.9±21.8 °C
Symbol GHS07
GHS07
Signal Word Warning

Mimicking peroxidase activity by a polymer-supported oxidovanadium(IV) Schiff base complex derived from salicylaldehyde and 1,3-diamino-2-hydroxypropane.

J. Inorg. Biochem. 147 , 181-92, (2015)

The polymer-supported oxidovanadium(IV) complex PS-[V(IV)O(sal-dahp)] (2) (PS=chloromethylated polystyrene crosslinked with 5% divinylbenzene, and H3sal-dahp=dibasic pentadentate ligand derived from salicylaldehyde and 1,3-diamino-2-hydroxypropane) was prepar...

Amino alcohol-based degradable poly(ester amide) elastomers.

Biomaterials 29(15) , 2315-25, (2008)

Currently available synthetic biodegradable elastomers are primarily composed of crosslinked aliphatic polyesters, which suffer from deficiencies including (1) high crosslink densities, which results in exceedingly high stiffness, (2) rapid degradation upon i...

Efficient gene transfection using novel cationic polymers poly(hydroxyalkylene imines).

Bioconjug. Chem. 21(9) , 1602-11, (2010)

A series of novel cationic polymers poly(hydroxyalkylene imines) were synthesized and tested for their ability to transfect cells in vitro and in vivo. Poly(hydroxyalkylene imines), in particular, poly(2-hydroxypropylene imine) (pHP), poly(2-hydroxypropylene ...

Copper(II) mediated anion dependent formation of Schiff base complexes.

Inorg. Chem. 44(11) , 3880-9, (2005)

A tetranuclear mixed ligand copper(II) complex of a pyrazole containing Schiff base and a hydroxyhexahydropyrimidylpyrazole and copper(II) and nickel(II) complexes of the Schiff base having N-donor atoms have been investigated. A 2 equiv amount of 5-methyl-3-...

Regulation of S-adenosylmethionine decarboxylase by polyamines in Ehrlich ascites-carcinoma cells grown in culture.

Biochem. J. 190(3) , 747-54, (1980)

1. The mechanism of stimulation of S-adenosylmethionine decarboxylase (EC 4.1.1.50) activity by inhibitors of ornithine decarboxylase (EC 4.1.1.17), namely dl-alpha-difluoromethylornithine, 1,3-diaminopropane and 1,3-diaminopropan-2-ol, was studied in Ehrlich...

Inhibition by derivatives of diguanidines of cell proliferation in Ehrlich ascites cells grown in cultures.

Biochem. J. 188(2) , 491-501, (1980)

The anti-proliferative effects of 1,1'-[(methylethanediylidene)dinitrilo]diguanidine [methylglyoxal bis(guanylhydrazone)] and 1,1'-[(metHYLETHANEDIYLIDENE)dinitrilo]bis-(3-aminoguaNIDINE) HAVE BEEN STUDIED IN Ehrlich ascites carcinoma cells grown in suspensio...

Regulation by 1,4-diamines of the ornithine decarboxylase activity induced by ornithine in perifused tumor cells.

Biochem. Pharmacol. 42(5) , 1045-52, (1991)

Ornithine decarboxylase (ODC) activity of Ehrlich carcinoma cells was increased more than 36-fold after being maintained for 3.5 hr in vitro in a special chamber which allowed continuous perifusion with 0.5 mM ornithine; if incubated in vitro without perifusi...

Dissociation between ornithine decarboxylase activity and aryl hydrocarbon hydroxylase induction in cell cultures treated with benz[a]anthracene and inhibitors of ornithine decarboxylase.

Biochem. Pharmacol. 31(2) , 189-93, (1982)

The induction of aryl hydrocarbon and ornithine decarboxylase by benz[a]-anthracene in the presence or absence of ornithine decarboxylase inhibitors was studied in three different cell culture systems. An almost complete abolishment of ornithine decarboxylase...

Regulation of tRNA methyltransferase activities by spermidine and putrescine. Inhibition of polyamine synthesis and tRNA methylation by alpha-methylornithine or 1,3-diaminopropan-2-ol in Dictyostelium.

Biochem. J. 202(1) , 153-62, (1982)

Inhibitors of polyamine synthesis (alpha-methylornithine and 1,3-diaminopropan-2-ol) were used to study the relationship between polyamine synthesis and specific methylations of tRNA in Dictyostelium discoideum during vegetative growth. Polyamine concentratio...

Spermidine level and protein synthesis are coregulated in nonproliferating hepatocytes.

Biol. Chem. Hoppe-Seyler 370(7) , 729-36, (1989)

The relationship between polyamines and the rate of protein synthesis was investigated in non-proliferating cells: primary cultures of adult rat hepatocytes maintained in serum-free media, and treated with dexamethasone or dexamethasone + insulin. During the ...