4-Acetylpyridine
4-Acetylpyridine structure
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Common Name | 4-Acetylpyridine | ||
|---|---|---|---|---|
| CAS Number | 1122-54-9 | Molecular Weight | 121.14 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 212.8±13.0 °C at 760 mmHg | |
| Molecular Formula | C7H7NO | Melting Point | 13-16 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 87.0±27.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Toward prediction of alkane/water partition coefficients.
J. Med. Chem. 51 , 3720-30, (2008) Partition coefficients were measured for 47 compounds in the hexadecane/water ( P hxd) and 1-octanol/water ( P oct) systems. Some types of hydrogen bond acceptor presented by these compounds to the partitioning systems are not well represented in the literatu... |
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The B vitamins nicotinamide (B3) and riboflavin (B2) stimulate metamorphosis in larvae of the deposit-feeding polychaete Capitella teleta: implications for a sensory ligand-gated ion channel.
PLoS ONE 9(11) , e109535, (2014) Marine sediments can contain B vitamins, presumably incorporated from settled, decaying phytoplankton and microorganisms associated with decomposition. Because B vitamins may be advantageous for the energetically intensive processes of metamorphosis, post-met... |
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Cyanoacetic acid hydrazones of 3-(and 4-)acetylpyridine and some derived ring systems as potential antitumor and anti-HCV agents.
Arch. Pharm. (Weinheim) 339(1) , 14-23, (2006) Two new acetylpyridinehydrazones derived from cyanoacetic acid hydrazide have been synthesized namely: cyanoacetic acid (1-pyridin-3 or 4-yl-ethylidene) hydrazides (1a,b). and some derived ring systems: 2-imino or 2-oxo-2H-chromenes (2a,b and 3a,b), substitut... |
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Characterization and biological studies on Co(II), Ni(II) and Cu(II) complexes of carbohydrazones ending by pyridyl ring.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 104 , 26-34, (2013) The chelating behavior of ligands based on carbohydrazone core modified with pyridine end towards Co(II), Ni(II) and Cu(II) ions have been examined. The ligands derived from the condensation of carbohydrazide with 2-acetylpyridine (H(2)APC) and 4-acetylpyridi... |
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Purification and characterization of rat liver enzyme catalyzing stereoselective reduction of acetylpyridines.
Chirality 17(8) , 494-500, (2005) Acetylpyridines (1-3) are known as aroma components of foods, perfumes, and smoking suppressants, showing several biological activities and constituting part of the structure of some important biologically active compounds. We purified and characterized an en... |
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Spectral studies of semicarbazones derived from 3- and 4-formylpyridine and 3- and 4-acetylpyridine: crystal and molecular structure of 3-formylpyridine semicarbazone.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 57(9) , 1847-54, (2001) Semicarbazones derived from 3- and 4-formylpyridine (H3FoPyS, H4FoPyS) and 3- and 4-acetylpyridine (H3AcPyS, H4AcPyS) were prepared and studied spectroscopically. Complete NMR assignments for these semicarbazones were made using DEPT135, as well as HMQC and H... |
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Novel trans-dichloridoplatinum(II) complexes with 3- and 4-acetylpyridine: Synthesis, characterization, DFT calculations and cytotoxicity.
Eur. J. Med. Chem. 44(5) , 1921-5, (2009) Novel complexes of platinum(II) with 3- (1) or 4-acetylpyridine (2) have been synthesized and characterized by elemental analyses, IR, (1)H and (13)C NMR spectroscopy. Single crystal X-ray diffraction revealed the trans geometry of complex 2. DFT calculations... |
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Effect of MK-801, kynurenate, glycine, dextrorphan and 4-acetylpyridine on striatal toxicity of quinolinate.
Brain Res. 481(2) , 356-60, (1989) Measurements of striatal choline acetyltransferase (ChAT) and glutamic acid decarboxylase (GAD) activities indicated that systemic administration of 4-8 mg/kg of MK-801 to rats completely blocked neuronal damage due to intrastriatal injections of 75-150 nmol ... |
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Catalytic properties of carbonyl reductase from rabbit liver for analogs of acetohexamide and 4-acetylpyridine.
Biochem. Mol. Biol. Int. 33(5) , 893-9, (1994) A correlation was observed between the values of specificity constant (kcat/Km) of carbonyl reductase from rabbit liver for acetohexamide analogs and their partition coefficients. This result indicates that the hydrophobicity in straight-chain alkyl groups of... |
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Normal coordinate analysis of 4-aminopyridine. Effect of substituent on pyridine ring in metal complexes of 4-substituted pyridines.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 57(7) , 1385-91, (2001) The normal coordinate analysis has been performed for 4-aminopyridine (4-apy) assuming C2v molecular symmetry. A Urey-Bradley force field has been used. The force constants are adjusted to fit the observed frequencies for 4-apy and its deuterated species. The... |