5-Iodosalicylic acid

5-Iodosalicylic acid Structure
5-Iodosalicylic acid structure
Common Name 5-Iodosalicylic acid
CAS Number 119-30-2 Molecular Weight 264.017
Density 2.2±0.1 g/cm3 Boiling Point 371.4±37.0 °C at 760 mmHg
Molecular Formula C7H5IO3 Melting Point 189-191 °C(lit.)
MSDS Chinese USA Flash Point 178.4±26.5 °C
Symbol GHS07
GHS07
Signal Word Warning

Iodination of salicylic acid improves its binding to transthyretin.

Biochim. Biophys. Acta 1784(3) , 512-7, (2008)

Transthyretin (TTR) is a plasma homotetrameric protein associated with senile systemic amyloidosis and familial amyloidotic polyneuropathy. In theses cases, TTR dissociation and misfolding induces the formation of amyloidogenic intermediates that assemble int...