dioxybenzone
dioxybenzone structure
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Common Name | dioxybenzone | ||
|---|---|---|---|---|
| CAS Number | 131-53-3 | Molecular Weight | 244.243 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 375.0±0.0 °C at 760 mmHg | |
| Molecular Formula | C14H12O4 | Melting Point | 73-75 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 146.0±18.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Metabolism of UV-filter benzophenone-3 by rat and human liver microsomes and its effect on endocrine-disrupting activity.
Toxicol. Appl. Pharmacol. 282(2) , 119-28, (2015) Benzophenone-3 (2-hydroxy-4-methoxybenzophenone; BP-3) is widely used as sunscreen for protection of human skin and hair from damage by ultraviolet (UV) radiation. In this study, we examined the metabolism of BP-3 by rat and human liver microsomes, and the es... |
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Oral chemoprevention of skin cancer in mice by benzophenone sunscreens dioxybenzone and octabenzone in drinking water.
Anticancer Res. 33(6) , 2535-40, (2013) Sunscreen compounds with added benefit of skin cancer prevention have both public and commercial interests. Our earlier study using the Epstein-Barr virus early antigen in vitro assay reported on skin cancer chemoprevention potential of benzophenone sunscreen... |
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Rapid determination of nine parabens and seven other environmental phenols in urine samples of German children and adults.
Int. J. Hyg. Environ. Health 217(8) , 845-53, (2014) We developed a fast, selective and sensitive on-line LC/LC-MS/MS method for the simultaneous determination of nine parabens and seven environmental phenols in urine. Parabens are widely used as antimicrobial preservatives. Bisphenol A, triclosan, triclocarban... |
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A novel two-dimensional liquid-chromatography method for online prediction of the toxicity of transformation products of benzophenones after water chlorination.
Anal. Bioanal. Chem 407 , 6137-48, (2015) Benzophenone-type UV filters (BPs) are ubiquitous in the environment. Transformation products (TPs) of BPs with suspected toxicity are likely to be produced during disinfection of water by chlorination. To quickly predict the toxicity of TPs, in this study, a... |
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Sensitive determination of salicylate and benzophenone type UV filters in water samples using solid-phase microextraction, derivatization and gas chromatography tandem mass spectrometry
Anal. Chim. Acta 638(1) , 36-44, (2009) A sensitive procedure for the determination of three UV filters: ethylhexyl salicylate (EHS), 3,3,5-trimethylcyclohexyl salicylate (Homosalate, HMS), 2-hydroxy-4-methoxybenzophenone (BP-3) and two related hydroxylated benzophenones (2,4-dihydroxybenzophenone,... |
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Reaction of benzophenone UV filters in the presence of aqueous chlorine: kinetics and chloroform formation.
Water Res. 47(2) , 579-87, (2013) The transformation of two benzophenone UV filters (Oxybenzone and Dioxybenzone) was examined over the pH range 6-11 in the presence of excess aqueous chlorine. Under these conditions, both UV filters were rapidly transformed by aqueous chlorine just above cir... |
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Synthesis and biological evaluation of novel N,N'-bis-methylenedioxybenzyl-alkylenediamines as bivalent anti-Alzheimer disease ligands.
J. Enzyme Inhib. Med. Chem. 26(5) , 706-11, (2011) A novel series of N,N'-bis-methylenedioxybenzyl-alkylenediamines 5a-5g have been designed, synthesized and evaluated as bivalent anti-Alzheimer's disease ligands. The enzyme inhibition assay results indicated that compounds 5e-5g inhibit both acetylcholineste... |
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Altered UV absorbance and cytotoxicity of chlorinated sunscreen agents.
Cutan. Ocul. Toxicol. 31(4) , 273-9, (2012) Sunscreens are widely utilized due to the adverse effects of ultraviolet (UV) radiation on human health. The safety of their active ingredients as well as that of any modified versions generated during use is thus of concern. Chlorine is used as a chemical di... |