Benzeneethanamine,N,N-dimethyl-
Benzeneethanamine,N,N-dimethyl- structure
|
Common Name | Benzeneethanamine,N,N-dimethyl- | ||
|---|---|---|---|---|
| CAS Number | 1126-71-2 | Molecular Weight | 149.23300 | |
| Density | 0.89g/mLat25ºC(lit.) | Boiling Point | 207-212ºC(lit.) | |
| Molecular Formula | C10H15N | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 159.8 °F | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Structure–activity correlations for β-phenethylamines at human trace amine receptor 1
Bioorg. Med. Chem. 16 , 7415-23, (2008) CoMFA 3D-QSAR studies on the potency of 68 β-phenethylamine analogs to activate hTAAR 1 (61% steric, 39% electrostatic) indicates that bulk both at nitrogen and 4-aryl leads to lower potency. |
|
|
Dissociative energy flow, vibrational energy redistribution, and conformeric structural dynamics in bifunctional amine model systems.
J. Phys. Chem. A 114(42) , 11078-84, (2010) Time-resolved multiphoton ionization mass spectrometry coupled with Rydberg Fingerprint Spectroscopy (RFS) has been used to analyze the structural and electronic dynamics of N,N-dimethylphenethylamine (PENNA) and N,N-dimethylcyclohexethylamine (CENNA). In PEN... |
|
|
[Development of positron tracer for in vivo estimation of brain MAO-B activity: theoretical consideration of metabolic-trapping tracers and evaluation of 11C-N,N dimethylphenylethylamine].
Kaku Igaku. 21(6) , 671-8, (1984)
|
|
|
The role of tear proteins in tear film stability in the dry eye patient and in the rabbit.
Adv. Exp. Med. Biol. 438 , 391-400, (1998)
|
|
|
Kinetics of [11C]N,N-dimethylphenylethylamine in mice and humans: potential for measurement of brain MAO-B activity.
J. Nucl. Med. 28(6) , 1006-11, (1987) Carbon-11-labeled N,N-dimethylphenylethylamine ([11C]DMPEA) was synthesized by the reaction of N-methylphenylethylamine with [11C]methyl iodide. This newly synthesized radiotracer was developed for the purpose of in vivo measurement of monoamine oxidase-B act... |
|
|
Radioactive N,N-dimethylphenylethylamine: a selective radiotracer for in vivo measurement of monoamine oxidase-B activity in the brain.
J. Neurochem. 44(1) , 210-6, (1985) N-[methyl-14C]N,N-dimethylphenylethylamine (DMPEA) was synthesized and its availability as a selective radiotracer for in vivo measurement of mouse brain monoamine oxidase (MAO) activity was examined. Relatively high incorporation of labelled DMPEA into brain... |
|
|
Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC-MS/MS.
Bioanalysis 3(24) , 2783-96, (2011) Low-dose methotrexate is used for the treatment of rheumatoid arthritis and juvenile idiopathic arthritis, but its effectiveness greatly varies between individuals. Therapeutic drug monitoring of intracellular methotrexate metabolites, the γ-polyglutamates (M... |
|
|
Tear film stability of protein extracts from dry eye patients administered a sigma agonist.
J. Ocul. Pharmacol. Ther. 13(2) , 151-61, (1997) Fourteen dry eye volunteers placed one to two drops of 0.15% AF2975 (N,N-dimethyl-2-phenylethylamine HCl) in one eye and the vehicle in their other eye four times a day for 21 days. AF2975 is a sigma agonist known to stimulate the release of tear proteins aft... |
|
|
The effects of sigma ligands on protein release from lacrimal acinar cells: a potential agonist/antagonist assay.
Life Sci. 56(15) , 1275-85, (1995) Sigma receptor antagonists have been proposed as leading clinical candidates for use in various psychotic disorders. Prior to clinical testing, it is imperative that a new agent be correctly identified as an antagonist and not an agonist since the latter may ... |
|
|
The influence of tear proteins on the film stability of rabbit tear extracts.
J. Ocul. Pharmacol. Ther. 14(1) , 15-29, (1998) This study was undertaken to gain an understanding of the significance of tear proteins in stabilizing the tear film. Either a sigma agonist, N,N-dimethyl-2-phenylethylamine HCl (AF2975), or a sigma antagonist, haloperidol, was administered to rabbit eyes in ... |