(-)-NOPOL

(-)-NOPOL Structure
(-)-NOPOL structure
Common Name (-)-NOPOL
CAS Number 35836-73-8 Molecular Weight 166.26000
Density 0.978g/cm3 Boiling Point 230ºC
Molecular Formula C11H18O Melting Point N/A
MSDS Chinese USA Flash Point 98.9ºC
Symbol GHS07
GHS07
Signal Word Warning

Acetyltransferase p300/CBP associated Factor (PCAF) regulates crosstalk-dependent acetylation of histone H3 by distal site recognition.

ACS Chem. Biol. 10(1) , 157-64, (2015)

Epigenetic regulation is directed, in part, by the correlated placement of histone post-translational modifications, but the mechanisms controlling correlated modifications are incompletely understood. Correlations arise from crosstalk among modifications and...

Development of novel formulations to enhance in vivo transdermal permeation of tocopherol.

Acta. Pharm. 64(3) , 299-309, (2014)

Tocopherol represents a big challenge for transdermal permeation owing to its extreme hydrophobicity and large molecular mass. The aim of the present study was to develop alpha-tocopherol (T) topical formulations and evaluate their ex vivo and in vivo permeat...

Kuwanon V inhibits proliferation, promotes cell survival and increases neurogenesis of neural stem cells.

PLoS ONE 10(2) , e0118188, (2015)

Neural stem cells (NSCs) have the ability to proliferate and differentiate into neurons and glia. Regulation of NSC fate by small molecules is important for the generation of a certain type of cell. The identification of small molecules that can induce new ne...

Differentiation of human umbilical cord matrix mesenchymal stem cells into neural-like progenitor cells and maturation into an oligodendroglial-like lineage.

PLoS ONE 9(10) , e111059, (2014)

Mesenchymal stem cells (MSCs) are viewed as safe, readily available and promising adult stem cells, which are currently used in several clinical trials. Additionally, their soluble-factor secretion and multi-lineage differentiation capacities place MSCs in th...

Biocompatible, biodegradable and porous liquid crystal elastomer scaffolds for spatial cell cultures.

Macromol. Biosci. 15(2) , 200-14, (2015)

Here we report on the modular synthesis and characterization of biodegradable, controlled porous, liquid crystal elastomers (LCE) and their use as three-dimensional cell culture scaffolds. The elastomers were prepared by cross-linking of star block-co-polymer...

Development of antibodies for determination of alkylresorcinol metabolites in human urine and elucidation of ELISA cross-reactivity.

J. Immunol. Methods 413 , 12-24, (2014)

Alkylresorcinols (ARs) are amphiphilic phenolic lipids and their two main metabolites, 3-(3,5-dihydroxyphenyl)-propanoic acid (DHPPA) and 3,5-dihydroxybenzoic acid (DHBA), can be used as biomarkers of whole grain wheat and rye intake. The aim of this study wa...

The biocompatibility of degradable magnesium interference screws: an experimental study with sheep.

Biomed Res. Int. 2015 , 943603, (2015)

Screws for ligament reconstruction are nowadays mostly made of poly-L-lactide (PLLA). However, magnesium-based biomaterials are gathering increased interest in this research field because of their good mechanical property and osteoanabolic influence on bone m...

Cell-penetrating antimicrobial peptides - prospectives for targeting intracellular infections.

Pharm. Res. 32(5) , 1546-56, (2015)

To investigate the suitability of three antimicrobial peptides (AMPs) as cell-penetrating antimicrobial peptides.Cellular uptake of three AMPs (PK-12-KKP, SA-3 and TPk) and a cell-penetrating peptide (penetratin), all 5(6)-carboxytetramethylrhodamine-labeled,...

Phenotypic and functional analysis of HL-60 cells used in opsonophagocytic-killing assay for Streptococcus pneumoniae.

J. Korean Med. Sci. 30(2) , 145-50, (2015)

Differentiated HL-60 is an effector cell widely used for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. We investigated the correlation between phenotypic expression of immunoreceptors and phagocytic ability of HL-60 c...

Lung deposition and cellular uptake behavior of pathogen-mimicking nanovaccines in the first 48 hours.

Adv. Healthc. Mater. 3(7) , 1071-7, (2014)

Pulmonary immunization poses the unique challenge of balancing vaccine efficacy with minimizing inflammation in the respiratory tract. While previous studies have shown that mice immunized intranasally with F1-V-loaded polyanhydride nanoparticles are protecte...