1-Hydroxybenzotriazole hydrate
1-Hydroxybenzotriazole hydrate structure
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Common Name | 1-Hydroxybenzotriazole hydrate | ||
|---|---|---|---|---|
| CAS Number | 123333-53-9 | Molecular Weight | 135.123 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 344.6±25.0 °C at 760 mmHg | |
| Molecular Formula | C6H5N3O | Melting Point | 155-158 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 162.2±23.2 °C | |
| Symbol |
GHS02 |
Signal Word | Warning | |
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Reduction of established antibody responses against botulinum neurotoxin A by synthetic monomethoxypolyethylene glycol peptide conjugates.
J. Neuroimmunol. 272(1-2) , 29-34, (2014) In cervical dystonia, injection of botulinum neurotoxin (BoNT) A or B into affected neck muscle reduces symptoms but may elicit anti-toxin antibodies (Abs) that block responsiveness to treatment. Previously, we localized the BoNT/A and BoNT/B sites that bind ... |
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Rational strategy for shaped nanomaterial synthesis in reverse micelle reactors.
Nat. Commun. 5 , 3870, (2014) The shape-controlled synthesis of nanoparticles was established in single-phase solutions by controlling growth directions of crystalline facets on seed nanocrystals kinetically; however, it was difficult to rationally predict and design nanoparticle shapes. ... |
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Cytocompatible in situ forming chitosan/hyaluronan hydrogels via a metal-free click chemistry for soft tissue engineering.
Acta Biomater. 20 , 60-8, (2015) Injectable hydrogels are important cell scaffolding materials for tissue engineering and regenerative medicine. Here, we report a new class of biocompatible and biodegradable polysaccharide hydrogels derived from chitosan and hyaluronan via a metal-free click... |
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Studies on the collision-induced dissociation of adipoR agonists after electrospray ionization and their implementation in sports drug testing.
J. Mass Spectrom. 50(2) , 407-17, (2015) AdipoR agonists are small, orally active molecules capable of mimicking the protein adiponectin, which represents an adipokine with antidiabetic and antiatherogenic effects. Two adiponectin receptors were reported in the literature referred to as adipoR1 and ... |
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Anti-Inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-Dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages.
PLoS ONE 10 , e0126871, (2015) Antimicrobial peptides (AMPs), also called host defense peptides, particularly those with amphipathic helical structures, are emerging as target molecules for therapeutic development due to their immunomodulatory properties. Although the antimicrobial activit... |
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Chemical synthesis of a polypeptide backbone derived from the primary sequence of the cancer protein NY-ESO-1 enabled by kinetically controlled ligation and pseudoprolines.
Biopolymers 104 , 116-27, (2015) The cancer protein NY-ESO-1 has been shown to be one of the most promising vaccine candidates although little is known about its cellular function. Using a chemical protein strategy, the 180 amino acid polypeptide, tagged with an arginine solubilizing tail, w... |
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Mobility of the Arg-Gly-Asp ligand on the outermost surface of biomaterials suppresses integrin-mediated mechanotransduction and subsequent cell functions.
Acta Biomater. 13 , 42-51, (2015) Mechanotransduction in the regulation of cellular responses has been previously studied using elastic hydrogels. Because cells interact only with the surface of biomaterials, we are focusing on the molecular mobility at the outermost surface of biomaterials. ... |
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Modification of daunorubicin-GnRH-III bioconjugates with oligoethylene glycol derivatives to improve solubility and bioavailability for targeted cancer chemotherapy.
Biopolymers 104 , 167-77, (2015) Daunorubicin-GnRH-III bioconjugates have recently been developed as drug delivery systems with potential applications in targeted cancer chemotherapy. In order to improve their biochemical properties, several strategies have been pursued: (1) incorporation of... |
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Investigation of dendriplexes by ion mobility-mass spectrometry.
Molecules 19(12) , 20731-50, (2014) Highly branched polyamidoamine (PAMAM) dendrimers presenting biological activities have been envisaged as non-viral gene delivery vectors. They are known to associate with nucleic acid (DNA) in non-covalent complexes via electrostatic interactions. Although t... |
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Tumor accumulation of protein kinase-responsive gene carrier/DNA polyplex stabilized by alkanethiol for intravenous injection.
J. Biomater. Sci. Polym. Ed. 26 , 657-68, (2015) We synthesized polymeric gene carriers consisting of poly-L-lysine (PLL) main chain modified both with substrate peptide for protein kinase Cα (PKCα) and alkanethiol (pentadecanethiol). Due to the grafted substrate peptide, the polyplex prepared from these ca... |