5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine
5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine structure
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Common Name | 5,10,15,20-Tetrakis(4-hydroxyphenyl)-21H,23H-porphine | ||
|---|---|---|---|---|
| CAS Number | 51094-17-8 | Molecular Weight | 678.733 | |
| Density | 1.4±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C44H30N4O4 | Melting Point | >300ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Iodinated hydroxyphenyl and hydroxynaphthyl porphyrins as tumour localisers.
Br. J. Cancer 61(5) , 687-8, (1990)
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Femtosecond dynamics of a porphyrin derivative confined by the human serum albumin protein.
J. Phys. Chem. B 114(49) , 16567-73, (2010) The relaxation dynamics of 5,10,15,20-tetrakis(4-hydroxyphenyl)-porphyrin (p-THPP) in tetrahydrofuran (THF) and encapsulated within the human serum albumin (HSA) protein in water solution was investigated. The protein environment affects the B→Q(y) and Q(x)→Q... |
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Preparation and characterization of sterile sub-200 nm meso-tetra(4-hydroxylphenyl)porphyrin-loaded nanoparticles for photodynamic therapy.
Eur. J. Pharm. Biopharm. 55(1) , 115-24, (2003) A photosensitizer, meso-tetra(4-hydroxyphenyl)porphyrin, was incorporated into sub-150 nm nanoparticles using the emulsification-diffusion technique in order to perform sterilization by filtration using 0.22 microm membranes. The three selected polyesters (po... |
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Enhanced photodynamic activity of meso-tetra(4-hydroxyphenyl)porphyrin by incorporation into sub-200 nm nanoparticles.
Eur. J. Pharm. Sci. 18(3-4) , 241-9, (2003) A photosensitizer, meso-tetra(hydroxyphenyl)porphyrin (p-THPP) was incorporated into sterile submicronic nanoparticles of poly(D,L-lactide-co-glycolide) (50:50 and 75:25 PLGA) and poly(D,L-lactide) (PLA). With all polymers used, sub-130 nm p-THPP-loaded nanop... |
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[Effects of para-tetra-hydroxyphenyl-porphyrin and red light on kidney clear cell carcinoma cells of Wistar rats].
Patol. Pol. 41(4) , 187-92, (1990) Results of investigation of para-tetra-hydroxyphenyl-porphyrin and red light on treatment of kidney clear cell carcinoma in Wistar rats have been assessed. Positive influence of photodynamic therapy was confirmed. |
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meso-Tetra(hydroxyphenyl)porphyrins, a new class of potent tumour photosensitisers with favourable selectivity.
Br. J. Cancer 54(5) , 717-25, (1986) We compared para-, meta- and ortho-isomers of meso-tetra(hydroxyphenyl)porphyrin (p-, m- and o-THPP) and the potassium salt of the para compound (K-p-THPP) with haematoporphyrin derivative (HpD) and Photofrin II in their ability to sensitise tumours, skin and... |
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Hydroporphyrins of the meso-tetra(hydroxyphenyl)porphyrin series as tumour photosensitizers.
Biochem. J. 261(1) , 277-80, (1989) Four new hydroporphyrins [the o, m and p isomers of 5,10,15,20-tetra(hydroxyphenyl)chlorin and 5,10,15,20-tetra(m-hydroxyphenyl)bacteriochlorin] related to the tetra(hydroxyphenyl)porphyrins have been prepared. They show the expected strong absorption bands i... |
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Novel nanostructural photosensitizers for photodynamic therapy: in vitro studies.
Int. J. Pharm. 430(1-2) , 129-40, (2012) Photosensitizing properties of 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin (p-THPP) functionalized by covalent attachment of one chain of poly(ethylene glycol) (PEG) with a molecular weight of 350, 2000, or 5000 Da (p-THPP-PEG(350), p-THPP-PEG(2000), p-THPP... |
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A high-performance and simple method for rapid and simultaneous determination of dihydroxybenzene isomers.
Analyst 137(4) , 944-52, (2012) A novel idea on the basis of 5,10,15,20-tetrakis(4-hydroxyphenyl)porphyrin (THPP) functionalized carbon nanotubes (CNTs) film was developed to simulate the chromatographic separation, which was able to rapidly and simultaneously detect dihydroxybenzene isomer... |
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A chemical dosimeter for the determination of the photodynamic activity of photosensitizers.
Clin. Chim. Acta 274(1) , 89-104, (1998) Uric acid a known singlet oxygen scavenger, was investigated as a chemical dosimeter in physiological aqueous solution for use in photodynamic therapy. The uric acid test takes the decrease in uric acid (UA) absorbance at 293 nm after laser light irradiation ... |