DISIALOGANGLIOSIDE GD1B 2NA
DISIALOGANGLIOSIDE GD1B 2NA structure
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Common Name | DISIALOGANGLIOSIDE GD1B 2NA | ||
|---|---|---|---|---|
| CAS Number | 19553-76-5 | Molecular Weight | 1854.08000 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C84H148N4O40 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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The role of sialyl glycan recognition in host tissue tropism of the avian parasite Eimeria tenella.
PLoS Pathog. 7(10) , e1002296, (2011) Eimeria spp. are a highly successful group of intracellular protozoan parasites that develop within intestinal epithelial cells of poultry, causing coccidiosis. As a result of resistance against anticoccidial drugs and the expense of manufacturing live vaccin... |
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High-throughput analysis of gangliosides in defined regions of fetal brain by fully automated chip-based nanoelectrospray ionization multi-stage mass spectrometry.
Eur. J. Mass Spectrom. (Chichester, Eng.) 15(4) , 541-53, (2009) Gangliosides (GGs), a large group of sialylated glycosphingolipids, are considered biomarkers of human brain development, aging and certain diseases. Determination of individual GG components in complex mixtures extracted from a human brain represents a funda... |
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Distribution of mono-, di- and trisialo gangliosides in the brain of Actinopterygian fishes
Biochim. Biophys. Acta 1820(9) , 1437-43, (2012) Background Mono-, di- and trisialo gangliosides are major glycosphingolipids in the brain of higher vertebrates involved in lipid raft assembly. In contrast, the fish brain is abundant in polisialo-gangliosides, whose function is implicated in the modulation ... |
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Glioma growth inhibition by neurostatin and O-But GD1b.
Neuro. Oncol. 12(11) , 1135-46, (2010) In spite of their low incidence, central nervous system tumors have elevated morbidity and mortality, being responsible for 2.3% of total cancer deaths. The ganglioside O-acetylated GD1b (O-Ac GD1b; neurostatin), present in the mammalian brain, and the semi-s... |
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GD1b-derived gangliosides modulate FcεRI endocytosis in mast cells.
J. Histochem. Cytochem. 59(4) , 428-40, (2011) The role of the mast cell-specific gangliosides in the modulation of the endocytic pathway of FcεRI was investigated in RBL-2H3 cells and in the ganglioside-deficient cell lines, E5 and D1. MAb BC4, which binds to the α subunit of FcεRI, was used in the analy... |
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The alpha-galactosyl derivatives of ganglioside GD(1b) are essential for the organization of lipid rafts in RBL-2H3 mast cells.
Exp. Cell Res. 314(13) , 2515-28, (2008) Gangliosides are complex glycosphingolipids that are important in many biological processes. The present study investigated the role of gangliosides in the organization of lipid rafts in RBL-2H3 mast cells and in the modulation of mast cell degranulation via ... |
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Novel antibodies reacting with two neighboring gangliosides are induced in rabbits immunized with bovine brain gangliosides.
Glycobiology 22(12) , 1768-74, (2012) Immunization of rabbits with bovine brain gangliosides induced an experimental neuropathy, with clinical signs resembling Guillain-Barré syndrome. All the immunized animals developed immunoglobulin G immunoreactivity to GM1 ganglioside. In a few (4 of 27) ani... |
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Nystagmus and ataxia associated with antiganglioside antibodies.
J. Neuroophthalmol. 31(4) , 326-30, (2011) Antiganglioside antibodies are found in various neurological disorders that constitute a continuum from peripheral neuropathy to encephalitis. However, nystagmus has rarely been described in patients with ataxia associated with antiganglioside antibodies.From... |
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Identification of gangliosides recognized by IgG anti-GalNAc-GD1a antibodies in bovine spinal motor neurons and motor nerves
Brain Res. 1227 , 216-20, (2008) The presence of immunoglobulin G (IgG)-type antibodies to the ganglioside, N-acetylgalactosaminyl GD1a (GalNAc-GD1a), is closely associated with the pure motor type of Guillain–Barré syndrome (GBS). In the present study, we isolated disialogangliosides from t... |
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Can subdural hematoma be a trigger for Guillain-Barré syndrome?
Int. J. Neurosci. 119(3) , 366-72, (2009) Guillain-Barré syndrome (GBS) is an acute inflammatory polyneuropathy which follows a precipitating event in approximately two thirds of cases. Although its pathogenesis is unclear, it is likely to be a consequence of an immune-mediated process. In the litera... |