PD 169316

PD 169316 Structure
PD 169316 structure
Common Name PD 169316
CAS Number 152121-53-4 Molecular Weight 360.341
Density 1.4±0.1 g/cm3 Boiling Point 583.1±50.0 °C at 760 mmHg
Molecular Formula C20H13FN4O2 Melting Point N/A
MSDS Chinese USA Flash Point 306.4±30.1 °C
Symbol GHS05 GHS06
GHS05, GHS06
Signal Word Danger

Inhibition of VEGF or TGF-{beta} signaling activates endothelium and increases leukocyte rolling.

Arterioscler. Thromb. Vasc. Biol. 29 , 1185-1192, (2009)

Motivated by the central roles that vascular endothelial growth factor (VEGF) and transforming growth factor (TGF)-beta play in the assembly and maintenance of the vasculature, we examined the impact of systemic VEGF or TGF-beta signal inhibition on endotheli...