salicyl alcohol
salicyl alcohol structure
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Common Name | salicyl alcohol | ||
|---|---|---|---|---|
| CAS Number | 90-01-7 | Molecular Weight | 124.137 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 238.6±7.0 °C at 760 mmHg | |
| Molecular Formula | C7H8O2 | Melting Point | 83-85 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 115.2±12.8 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Cellular apoptosis and cytotoxicity of phenolic compounds: a quantitative structure-activity relationship study.
J. Med. Chem. 48 , 7234-42, (2005) In this comprehensive study on the caspase-mediated apoptosis-inducing effect of 51 substituted phenols in a murine leukemia cell line (L1210), we determined the concentrations needed to induce caspase activity by 50% (I50) and utilized these data to develop ... |
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Functional characterization of two acyltransferases from Populus trichocarpa capable of synthesizing benzyl benzoate and salicyl benzoate, potential intermediates in salicinoid phenolic glycoside biosynthesis.
Phytochemistry 113 , 149-59, (2015) Salicinoids are phenolic glycosides (PGs) characteristic of the Salicaceae and are known defenses against insect herbivory. Common examples are salicin, salicortin, tremuloidin, and tremulacin, which accumulate to high concentrations in the leaves and bark of... |
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Salicyl alcohol oxidase of the chemical defense secretion of two chrysomelid leaf beetles. Molecular and functional characterization of two new members of the glucose-methanol-choline oxidoreductase gene family.
J. Biol. Chem. 283(28) , 19219-28, (2008) Salicyl alcohol oxidase is an extracellular enzyme that occurs in glandular reservoirs of chrysomelid leaf beetle larvae and catalyzes the formation of salicylaldehyde, a volatile deterrent used by the larvae against predators. Salicyl alcohol is the hydrolys... |
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Rapid syntheses of benzopyrans from o-OBOC salicylaldehydes and salicyl alcohols: a three-component reaction.
J. Org. Chem. 67(20) , 6911-5, (2002) The Diels-Alder reactions of o-quinone methides generated from OBOC-salicylic aldehydes and alcohols are described, allowing for the synthesis of various substituted benzopyrans. The low temperatures employed for this procedure enable high diastereoselectivit... |
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Enzymatic synthesis of two salicin analogues by reaction of salicyl alcohol with Bacillus macerans cyclomaltodextrin glucanyltransferase and Leuconostoc mesenteroides B-742CB dextransucrase.
Carbohydr. Res. 339(8) , 1517-29, (2004) Beta-Salicin is a naturally occurring glycoside found in the bark of poplar and willow trees. Ancient man used it as an analgesic and antipyretic. It has a D-glucopyranose unit attached by a beta-linkage to the phenolic hydroxyl of salicyl alcohol. Two new sa... |
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Precise RNAi-mediated silencing of metabolically active proteins in the defence secretions of juvenile leaf beetles.
Proc. Biol. Sci. 279(1745) , 4126-34, (2012) Allomones are widely used by insects to impede predation. Frequently these chemical stimuli are released from specialized glands. The larvae of Chrysomelina leaf beetles produce allomones in gland reservoirs into which the required precursors and also the enz... |
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Predicting the substrate specificity of a glycosyltransferase implicated in the production of phenolic volatiles in tomato fruit.
FEBS J. 278(2) , 390-400, (2011) The volatile compounds that constitute the fruit aroma of ripe tomato (Solanum lycopersicum) are often sequestered in glycosylated form. A homology-based screen was used to identify the gene SlUGT5, which is a member of UDP-glycosyltransferase 72 family and s... |
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Predicting mixture toxicity of seven phenolic compounds with similar and dissimilar action mechanisms to Vibrio qinghaiensis sp.nov.Q67.
Ecotoxicol. Environ. Saf. 74(6) , 1600-6, (2011) The predictions of mixture toxicity for chemicals are commonly based on two models: concentration addition (CA) and independent action (IA). Whether the CA and IA can predict mixture toxicity of phenolic compounds with similar and dissimilar action mechanisms... |
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Evaluation of salicin as an antipyretic prodrug that does not cause gastric injury.
Planta Med. 68(8) , 714-8, (2002) Pharmacokinetic and pharmacological studies were performed to compare the antipyretic effects of salicin (SL), saligenin (SG, an aglycone of SL) and salicylic acid (SA, an active metabolite of SL) in rats. When SL was administered orally to rats, SA appeared ... |
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Monitoring carbohydrate enzymatic reactions by quantitative in vitro microdialysis.
J. Chromatogr. A. 1118(1) , 125-33, (2006) On-line in vitro microdialysis (MD) sampling followed by HPLC separation and UV absorbance detection (HPLC-UV) was used to monitor carbohydrate enzyme systems. Fundamental parameters (i.e., K(m) and V(max)) of hydrolysis reactions of 4-nitrophenyl-beta-D-gluc... |