1-Nitropropane
1-Nitropropane structure
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Common Name | 1-Nitropropane | ||
|---|---|---|---|---|
| CAS Number | 108-03-2 | Molecular Weight | 89.093 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 131.7±3.0 °C at 760 mmHg | |
| Molecular Formula | C3H7NO2 | Melting Point | -108 °C | |
| MSDS | Chinese USA | Flash Point | 33.9±0.0 °C | |
| Symbol |
GHS02, GHS06 |
Signal Word | Danger | |
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Development of a standard gas generating vial comprised of a silicon oil-polystyrene/divinylbenzene composite sorbent.
J. Chromatogr. A. 1410 , 1-8, (2015) In this work, a highly reproducible standard gas generating vial is proposed. The vial is comprised of a silicon diffusion pump oil spiked with an appropriate calibration compound, such as modified McReynolds probes (benzene, 2-pentanone, pyridine, 1-nitropro... |
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Performance of graphene sheets as stationary phase for capillary gas chromatographic separations.
J. Chromatogr. A. 1399 , 74-9, (2015) This work presents the investigation of graphene as a new type of stationary phase for capillary GC separations. Graphene capillary column (0.25 mm, i.d.) achieved column efficiency of 3100 plates/m determined by n-dodecane at 120 °C. The obtained McReynolds ... |
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Spin trapping of nitric oxide by aci anions of nitroalkanes.
Nitric Oxide 10(2) , 53-9, (2004) In alkaline solutions, nitroalkanes (RCH2NO2) undergo deprotonation and rearrange to an aci anion (RHC=NO2-), which may function as a spin trap. Using electron paramagnetic resonance (EPR) spectroscopy, we have investigated suitability of aci anions of a seri... |
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Disposition and metabolism of 1-nitropropane in rats and chimpanzees.
Biomed. Environ. Sci. 2(3) , 249-64, (1989) The metabolic fate of 1-nitropropane (1-NP) has not been previously reported. In this study male rats and chimpanzees were given single doses of 40 mg/kg ip and 5 mg/kg iv 1-[1-14C]NP, respectively. The quantitative extent of urinary and fecal elimination was... |
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[Investigation on the changing regularity of the relationship between retention index and temperature of the GDX series stationary phases].
Se Pu 18(2) , 128-30, (2000) A systematical measure of the polarity scale of the Chinese porous polymer beads of this series of stationary phase has been carried out, including the McReynolds constant at 120 degrees C by using squalane as non-polar stationary phase and the relative const... |
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Differing actions of nitropropane analogs of GABA and baclofen in central and peripheral preparations.
Eur. J. Pharmacol. 264(1) , 49-54, (1994) In the guinea-pig isolated ileum, both baclofen (5-100 microM) and gamma-aminobutyric acid (GABA; 5-100 microM) induced a bicuculline-insensitive depression of cholinergic twitch contractions which was reversibly and competitively antagonised by 3-amino-1-nit... |
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Micronucleus test in bone marrow of mice treated with 1-nitropropane, 2-nitropropane and cisplatin.
Mutat. Res. 192(3) , 181-4, (1987) Micronucleus tests were carried out in bone marrow of mice treated with 1-nitropropane, 2-nitropropane and cisplatin. For 1-nitropropane and 2-nitropropane the results were negative. With cisplatin a dose-dependent increase in the number of polychromatic eryt... |
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Relationship of hepatocarcinogenicity and hepatocellular proliferation induced by mutagenic noncarcinogens vs carcinogens. II. 1- vs 2-nitropropane.
Toxicol. Appl. Pharmacol. 110(3) , 505-13, (1991) 2-Nitropropane (2-NP) is mutagenic in a number of short-term mutagenicity assays in vitro and in vivo, and is a potent hepatocarcinogen in rats. A structural isomer, 1-nitropropane (1-NP), is mutagenic in V79 cells and can induce unscheduled DNA synthesis in ... |
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Assay of 1-nitropropane, 2-nitropropane, 1-azoxypropane and 2-azoxypropane for carcinogenicity by gavage in Sprague-Dawley rats.
Carcinogenesis 8(12) , 1947-9, (1987) 1-Nitropropane (1-NP), 2-nitropropane (2-NP), 1-azoxypropane (1-AP) and 2-azoxypropane (2-AP), were assayed for carcinogenicity by gavage in male Sprague-Dawley rats. 2-NP was given at 1 mmol/kg three times per week for 16 weeks. 1-NP (1 mmol/kg), 1-AP (0.1 m... |
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Involvement of different pathways in the genotoxicity of nitropropanes in cultured mammalian cells.
Mutagenesis 5(4) , 375-80, (1990) The metabolic pathways leading to genotoxicity of nitropropanes in mammalian cells were investigated by measuring the effects of 2-nitropropane (2-NP) and 1-nitropropane (1-NP) on various cell lines characterized for their expression of cytochrome P450-depend... |