3,3-Diphenylpropylamine

3,3-Diphenylpropylamine Structure
3,3-Diphenylpropylamine structure
Common Name 3,3-Diphenylpropylamine
CAS Number 5586-73-2 Molecular Weight 211.302
Density 1.0±0.1 g/cm3 Boiling Point 331.9±31.0 °C at 760 mmHg
Molecular Formula C15H17N Melting Point 29-31 °C(lit.)
MSDS Chinese USA Flash Point 155.2±17.0 °C
Symbol GHS07
GHS07
Signal Word Warning

(Bis)urea and (bis)thiourea inhibitors of lysine-specific demethylase 1 as epigenetic modulators.

J. Med. Chem. 53(14) , 5197-212, (2010)

The recently discovered enzyme lysine-specific demethylase 1 (LSD1) plays an important role in the epigenetic control of gene expression, and aberrant gene silencing secondary to LSD1 overexpression is thought to contribute to the development of cancer. We re...

Determination of the D- and L-enantiomers of modafinil in human plasma utilizing liquid-liquid extraction and high-performance liquid chromatography.

J. Chromatogr. B. Biomed. Sci. Appl. 730(1) , 1-7, (1999)

Modafinil, DL-2-[(diphenylmethyl)sulfinyl]acetamide (Provigil), which is chiral at its sulfur atom, is a novel wake-promoting agent currently being developed as the racemate in the United States by Cephalon, Inc. In order to characterize the pharmacokinetic p...

NPS 1506, a novel NMDA receptor antagonist and neuroprotectant. Review of preclinical and clinical studies.

Ann. N. Y. Acad. Sci. 890 , 450-7, (1999)

NPS 1506 is a moderate affinity, uncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist. NPS 1506 is neuroprotective in rodent models of ischemic stroke, hemorrhagic stroke, and head trauma, with a 2-hr window of opportunity. Neuroprotectant doses of N...

In vitro inhibition of rat small intestinal absorption by lipophilic organic cations.

Biochim. Biophys. Acta 813(1) , 25-32, (1985)

Cationic, lipid-soluble organic compounds may interfere with cation-mediated membrane transport processes. Thus, small intestinal absorption may be influenced by lipophilic organic cations. Therefore a series of arylalkylamines was studied in the concentratio...

Binding of 2,2-diphenylpropylamine at the aldehyde site of bacterial luciferase increases the affinity of the reduced riboflavin 5'-phosphate site.

Biochemistry 20(19) , 5524-8, (1981)

We have found a new class of inhibitors of the bacterial bioluminescence reaction, the N,N-diphenylalkylamines and acids. We have studied the action of one of these compounds 2,2-diphenylpropylamine. The amine was competitive with the long-chain aliphatic ald...