Ethylhydrocupreine

Ethylhydrocupreine Structure
Ethylhydrocupreine structure
Common Name Ethylhydrocupreine
CAS Number 522-60-1 Molecular Weight 340.45900
Density 1.18g/cm3 Boiling Point 508.7ºC at 760mmHg
Molecular Formula C21H28N2O2 Melting Point 123-128° when solvent-free
MSDS Chinese USA Flash Point 261.5ºC
Symbol GHS07
GHS07
Signal Word Warning

Identifying mutator phenotypes among fluoroquinolone-resistant strains of Streptococcus pneumoniae using fluctuation analysis.

Antimicrob. Agents Chemother. 51 , 3225-9, (2007)

The occurrence of mutator phenotypes among laboratory-generated and clinical levofloxacin-resistant strains of Streptococcus pneumoniae was determined using fluctuation analysis. The in vitro selection for levofloxacin-resistant mutants of strain D39, each wi...

Genotypic identification of presumptive Streptococcus pneumoniae by PCR using four genes highly specific for S. pneumoniae.

J. Med. Microbiol. 55(Pt 6) , 709-14, (2006)

It was previously reported that two oligonucleotide primer sets (spn9802 and spn9828) for discriminating Streptococcus pneumoniae from pneumococcus-like oral streptococcal isolates using PCR had been developed. In this study, PCR amplification of the lytA, pl...

Possible overestimation of penicillin resistant Streptococcus pneumoniae colonization rates due to misidentification of oropharyngeal streptococci.

Diagn. Microbiol. Infect. Dis. 42(4) , 263-8, (2002)

Standard identification of Streptococcus pneumoniae by optochin and bile solubility testing can lead to ambiguous results for certain isolates. Newer bacteriologic identification techniques (e.g., DNA probes) now exist. In a prospective point prevalence study...

Characterization of in vitro-generated and clinical optochin-resistant strains of Streptococcus pneumoniae isolated from Argentina.

J. Clin. Microbiol. 46(6) , 1930-4, (2008)

Optochin susceptibility is a key test used for pneumococcal diagnosis, but optochin-resistant (Opt(r)) pneumococci have been reported in the last 2 decades. In this work, we characterized eight Opt(r) clinical strains which presented a new mutation, G47V, a p...

Diversity of mutations in the atpC gene coding for the c Subunit of F0F1 ATPase in clinical isolates of optochin-resistant Streptococcus pneumoniae from Brazil.

J. Clin. Microbiol. 45(9) , 3065-7, (2007)

We report the characteristics of four optochin-resistant (Opt(r)) Streptococcus pneumoniae isolates from Brazil. All four Opt(r) isolates presented mutations in the nucleotide sequence coding for the c subunit of F(0)F(1) ATPase. Two isolates showed mutations...

Emergence of optochin resistance among Streptococcus pneumoniae in Portugal.

Microb. Drug Resist. 12(4) , 239-45, (2006)

In most clinical microbiology laboratories optochin susceptibility is used in the screening and identification of Streptococcus pneumoniae. We report the characterization of 32 optochin-resistant S. pneumoniae strains from 10 laboratories that constituted 3.2...

Phenotypic and genotypic discrepancy of Streptococcus pneumoniae strains isolated from Asian countries.

FEMS Immunol. Med. Microbiol. 45(1) , 63-70, (2005)

Non-typeable isolates of Streptococcus pneumoniae collected from Asian countries were characterized by optochin susceptibility test, bile solubility test, multilocus sequence typing of housekeeping genes, amplification of virulence-related genes, 16S rDNA-Rsa...

Optochin resistance in Streptococcus pneumoniae induced by frozen storage in glycerol.

Diagn. Microbiol. Infect. Dis. 58(2) , 185-90, (2007)

Susceptibility to optochin is frequently the only test used to differentiate Streptococcus pneumoniae from other alpha-hemolytic streptococci isolated from clinical specimens. The current study shows that storage of S. pneumoniae isolates in tryptic soy broth...

A novel mutation in the alpha-helix 1 of the C subunit of the F(1)/F(0) ATPase responsible for optochin resistance of a Streptococcus pneumoniae clinical isolate.

Diagn. Microbiol. Infect. Dis. 38(2) , 119-21, (2000)

Previously reported mutations involved in optochin resistance of Streptococcus pneumoniae clinical isolates changed residues 48, 49 or 50, in the transmembrane alpha-helix 2 of the F(1)/F(0) ATPase subunit. We report here an unusual mutation which changes the...

Empyema caused by optochin sensitive Streptococcus mitis in the course of varicella.

Indian J. Pediatr. 77(4) , 464, (2010)