2-AMINO-4-PENTENOIC ACID HYDROCHLORIDE
2-AMINO-4-PENTENOIC ACID HYDROCHLORIDE structure
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Common Name | 2-AMINO-4-PENTENOIC ACID HYDROCHLORIDE | ||
|---|---|---|---|---|
| CAS Number | 7685-44-1 | Molecular Weight | 115.131 | |
| Density | 1.0±0.1 g/cm3 | Boiling Point | 222.7±23.0 °C at 760 mmHg | |
| Molecular Formula | C5H9NO2 | Melting Point | 251-253ºC | |
| MSDS | Chinese USA | Flash Point | 88.5±22.6 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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In vivo neurochemical evidence that newly synthesised GABA activates GABA(B), but not GABA(A), receptors on dopaminergic nerve endings in the nucleus accumbens of freely moving rats.
Neuropharmacology 62 , 907-913, (2012) GABA released from accumbal GABAergic interneurons plays an inhibitory role in the regulation of dopamine efflux through GABA(B) and GABA(A) receptors located on accumbal dopaminergic nerve endings. The cytosolic newly synthesised GABA alters vesicular GABA l... |
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Cyclic opioid peptide agonists and antagonists obtained via ring-closing metathesis.
Chem. Biol. Drug Des. 74 , 329-334, (2009) The opioid peptide H-Tyr-c[D-Cys-Phe-Phe-Cys]NH(2) cyclized via a methylene dithiother is a potent and selective mu opioid agonist (Przydial M.J. et al., J Peptide Res, 66, 2005, 255). Dicarba analogues of this peptide with Tyr, 2',6'-dimethyltyrosine (Dmt), ... |
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Disruption of GABAergic tone in the dorsomedial hypothalamus attenuates responses in a subset of serotonergic neurons in the dorsal raphe nucleus following lactate-induced panic.
J. Psychopharmacol. 22 , 642-652, (2008) Panic patients are vulnerable to induction of panic attacks by sub-threshold interoceptive stimuli such as intravenous (i.v.) sodium lactate infusions. Facilitation of serotonergic signaling with selective serotonin reuptake inhibitors can suppress anxiety an... |
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Metabolism of allylglycine and cis-crotylglycine by Pseudomonas putida (arvilla) mt-2 harboring a TOL plasmid.
J. Bacteriol. 148 , 72-82, (1981) Spontaneous mutants which acquired the ability to utilize d-allylglycine (d-2-amino-4-pentenoic acid) and dl-cis-crotylglycine (dl-2-amino-cis-4-hexenoic acid) but not l-allylglycine or dl-trans-crotylglycine could be readily isolated from Pseudomonas putida ... |
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Allylglycine and brain excitability. Electrophysiological investigation in cats.
Acta Physiol. Pharmacol. Bulg. 15 , 47-53, (1989) The effect of DL-allylglycine (DL-AG) in two doses (40 and 60 mg/kg i.v.) was studied on cats under acute conditions. DL-AG provoked the appearance of epileptiform EEG patterns either spontaneous or in response to intermittent light stimulation with a frequen... |
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In vivo modulation of benzodiazepine receptor function after inhibition of endogenous gamma-aminobutyyric acid synthesis.
Eur. J. Pharmacol. 321 , 13, (1997) The influence of decreased endogenous gamma-aminobutyric acid (GABA) concentration on benzodiazepine receptor function was studied in the brain of living baboons. Positron emission tomography and the radiotracer [11C]flumazenil combined with electroencephalog... |
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Non-centrosymmetric racemates: space-group frequencies and conformational similarities between crystallographically independent molecules. Dalhus B, Görbitz CH.
Acta Physiol. Pharmacol. Bulg. 56 , 715-719, (2000)
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